CAR-T\u7d30\u80de\u7642\u6cd5\u306f\u73fe\u5728\u7b2c3\u4e16\u4ee3\u306e\u3088\u3046\u3067\u3059\u3002
\nhttps:\/\/www.cancer.gov\/about-cancer\/treatment\/research\/car-t-cells
\n\u304c\u3093\u7d30\u80de\u306e\u8868\u9762\u306b\u3042\u308b\u60c5\u5831\u4f1d\u9054\u90e8\u4f4d\uff08\u2190\u3053\u308c\u304c\u4f55\u306a\u306e\u304b\u306f\u660e\u65e5\u8aac\u660e\u3057\u307e\u3059\uff09\u306b\u7d50\u5408\u3059\u308b\u6297\u4f53\u533b\u85ac\u54c1\u306f\u5206\u5b50\u6a19\u7684\u85ac\u3068\u3057\u3066\u5b9f\u7528\u5316\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u9ad8\u4fa1\u306a\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3092\u4f55\u56de\u3082\u6295\u4e0e\u3057\u306a\u3044\u3068\u3044\u3051\u307e\u305b\u3093\u3002\u60a3\u8005\u81ea\u8eab\u306e\u30ad\u30e9\u30fcT\u7d30\u80de\u306b\u304c\u3093\u7d30\u80de\u3092\u8a8d\u8b58\u3059\u308b\u6297\u4f53\u3092\u304f\u3063\u3064\u3051\u3066\u3057\u307e\u3048\u3070\u305f\u304f\u3055\u3093\u653b\u6483\u3067\u304d\u308b\u3060\u308d\u3046\u3001\u3068\u3044\u3046\u306e\u304c\u57fa\u672c\u3067\u3059\u3002\u30ad\u30e9\u30fc\uff34\u7d30\u80de\u306f\u9069\u5207\u306a\u4fe1\u53f7\u3092\u3082\u3089\u3046\u3068\u653b\u6483\u30e2\u30fc\u30c9\u306b\u306a\u308a\u307e\u3059\u3002\u4e0a\u8a18\u8a18\u4e8b\u306b\u3042\u308b\u3088\u3046\u306b\u3001CAR-T\u7d30\u80de\u306f\u304c\u3093\u7d30\u80de\u306e\u8868\u9762\u3092\u8a8d\u8b58\u3059\u308b\u6297\u4f53\u3068\u3001\u653b\u6483\u30e2\u30fc\u30c9\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u67d4\u8edf\u6027\u306e\u3042\u308b\u30ea\u30f3\u30ab\u30fc\u3067\u3064\u306a\u3044\u3067\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u306a\u306e\u3067\u3001\u7d50\u5c40\u306e\u3068\u3053\u308d\uff34\u7d30\u80de1\u500b\u5f53\u305f\u308a\u306b10\u4e07\u500b\u51fa\u3066\u3044\u308b\u30b9\u30a4\u30c3\u30c1\u306e\u7d10\u3092\u5f15\u3063\u5f35\u308b\u3088\u3046\u306a\u52d5\u304d\u3092\u3059\u308b\u3068\u653b\u6483\u30e2\u30fc\u30c9\u306b\u5165\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3044\u307e\u3059\u3002\u7b2c\uff11\u4e16\u4ee3\u306f\u30a8\u30a4\u30ba\u306e\u6cbb\u7642\u306b\u4f7f\u304a\u3046\u3068\u3057\u307e\u3057\u305f\u304c\u52b9\u679c\u304c\u306a\u304f\u3001\u7b2c\u4e8c\u4e16\u4ee3\u3067\uff34\u7d30\u80de\u306e\u4e2d\u306b\u5165\u3063\u3066\u3044\u308b\u653b\u6483\u30e2\u30fc\u30c9\u306e\u30b9\u30a4\u30c3\u30c1\uff08\u5f15\u3063\u5f35\u3089\u308c\u308b\u3068\u52d5\u4f5c\u3059\u308b\uff09\u3092\uff12\u6bb5\u306b\u3057\u305f\u3089\u3046\u307e\u304f\u3044\u304f\u3088\u3046\u306b\u306a\u308a\u3001\u73fe\u5728\u306f\u3055\u3089\u306b\u6539\u826f\u3055\u308c\u3066\u7b2c\uff13\u4e16\u4ee3\u306e\u3088\u3046\u3067\u3059\u3002\u4f53\u5185\u3067\u306f\u7d30\u80de\u304c\u300c\u304a\u3057\u304f\u3089\u307e\u3093\u3058\u3085\u3046\u300d\u3092\u3057\u3066\u3044\u3066\u3001\u3044\u307c\u3044\u307c\u306e\u3064\u3044\u305f\u7403\u5f62\u306eT\u7d30\u80de\u304c\u4ed6\u306e\u7d30\u80de\u3092\u3042\u3061\u3053\u3061\u89e6\u3063\u3066\u3001\u3044\u307c\u3044\u307c\u3088\u308a\u305a\u3063\u3068\u5c0f\u3055\u304410\u4e07\u500b\u3042\u308b\u89e6\u624b\u304c\u304f\u3063\u3064\u3044\u3066\u5f15\u3063\u5f35\u3089\u308c\u3001\u3042\u308b\u7a0b\u5ea6\u306e\u6570\u304c\u9023\u7d9a\u3067\u5f15\u3063\u5f35\u3089\u308c\u308b\u3068\u653b\u6483\u30e2\u30fc\u30c9\u306b\u306a\u308b\u3001\u3068\u3044\u3046\u4ed5\u7d44\u307f\u306e\u3088\u3046\u306b\u601d\u3048\u307e\u3059\u3002\u305d\u3046\u8003\u3048\u308b\u3068\uff34\u7d30\u80de\u306e\u5f62\u306f\u5408\u7406\u7684\u3067\u3059\u306d\u3002
\n\u82f1\u8a9e\u306f\u3000https:\/\/www.cancer.gov\/about-cancer\/treatment\/research\/car-t-cells<\/p>\n
\u201dFor decades, the foundations of cancer treatment have been surgery, chemotherapy, and radiation therapy.\u201d
\nfor decades \u30c7\u30a3\u300c\u30b1\u300d\u30a4\u30c5\u3000\u4f55\u5341\u5e74\u3082\u306e\u9593
\nfoundations \u57fa\u672c
\ntreatment \u6cbb\u7642
\nsurgery \u300c\u30b5\u300d\u30fc\u30b8\u30a7\u30ea\u3000\u5916\u79d1\u624b\u8853
\nchemotherapy \u5316\u5b66\u7642\u6cd5
\nradiation therapy \u653e\u5c04\u7dda\u7642\u6cd5
\n“The 2000s marked the emergence of targeted therapies like imatinib (Gleevec) and trastuzumab (Herceptin)\u2014drugs that find and kill cancer cells by homing in on specific molecular changes seen primarily in those cells. ”
\nThe 2000s 2000\u5e74\u4ee3
\nemergence \u767b\u5834
\nhome in \u7684\u3092\u7d5e\u308b\u3001\u91ce\u7403\u3067\u30db\u30fc\u30e0\u30a4\u30f3\u3059\u308b
\n-nib \u5c0f\u5206\u5b50\u578b\u306e\u5206\u5b50\u6a19\u7684\u85ac\u306b\u3064\u3051\u308b\u8a9e\u5c3e\u3002 -ib\u306f\u9175\u7d20\u963b\u5bb3\u5264\u306b\u7740\u3051\u308b\u8a9e\u5c3e\u3067\u3001-nib\u306e\u5834\u5408\u3082\u3042\u308b\u306e\u3067\u3084\u3084\u3053\u3057\u3044\u3002
\n-mab\u3000\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\uff08\u5206\u5b50\u91cf140000\u7a0b\u5ea6\u3001\u907a\u4f1d\u5b50\u5de5\u5b66\u3067\u4f5c\u3089\u308c\u308b\uff09\u3092\u8868\u3059\u8a9e\u5c3e\u3002
\nprimarily \u3000\u7c73\u3000\u30d7\u30e9\u30a4\u300c\u30de\u300d\u30ea\u308a\u3000\u82f1\u3000\u300c\u30d7\u300d\u30e9\u30a4\u30de\u30ea\u308a\u3000\u3000\u79c1\u306f\u300c\u7c73\u5f0f\u300d\u3067\u767a\u97f3\u3057\u307e\u3059\u3002
\n“More than 80% of children diagnosed with ALL that arises in B cells, the predominant type of pediatric ALL, will be cured by intensive chemotherapy. But effective treatments have been limited for patients whose cancers return, or relapse, after chemotherapy or a stem-cell transplant.”
\nALL = acute lyphoblastic leuchemia \u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5
\npediatric \u30da\u30c7\u30a3\u300c\u30a2\u300d\u30c8\u30ea\u30c3\u30af\u3000\u5c0f\u5150\u306e\u3001\u5c0f\u5150\u79d1
\nrelapse \u30ea\u300c\u3089\u300d\u30d7\u30b9\u3000\u4e00\u65e6\u3088\u304f\u306a\u3063\u3066\u518d\u3073\u60aa\u5316\u3059\u308b\u3053\u3068
\na stem-cell transplant \u5e79\u7d30\u80de\u79fb\u690d\uff08\u3044\u308f\u3086\u308b\u9aa8\u9ac4\u79fb\u690d\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"
CAR-T\u7d30\u80de\u7642\u6cd5\u306f\u73fe\u5728\u7b2c3\u4e16\u4ee3\u306e\u3088\u3046\u3067\u3059\u3002 https:\/\/www.cancer.gov\/about-cancer\/treatment\/research\/car-t-cells \u304c\u3093\u7d30\u80de\u306e\u8868\u9762\u306b\u3042\u308b\u60c5\u5831\u4f1d\u9054\u90e8\u4f4d\uff08\u2190\u3053\u308c\u304c\u4f55\u306a\u306e\u304b\u306f\u660e\u65e5\u8aac\u660e\u3057\u307e\u3059\uff09\u306b\u7d50\u5408\u3059\u308b\u6297\u4f53\u533b\u85ac\u54c1\u306f\u5206\u5b50\u6a19\u7684\u85ac\u3068\u3057\u3066\u5b9f\u7528\u5316\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u9ad8\u4fa1\u306a\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3092\u4f55\u56de\u3082\u6295\u4e0e\u3057\u306a\u3044\u3068\u3044\u3051\u307e\u305b\u3093\u3002\u60a3\u8005\u81ea\u8eab\u306e\u30ad\u30e9\u30fcT\u7d30\u80de\u306b\u304c\u3093\u7d30\u80de\u3092\u8a8d\u8b58\u3059\u308b\u6297\u4f53\u3092\u304f\u3063\u3064\u3051\u3066\u3057\u307e\u3048\u3070\u305f\u304f\u3055\u3093\u653b\u6483\u3067\u304d\u308b\u3060\u308d\u3046\u3001\u3068\u3044\u3046\u306e\u304c\u57fa\u672c\u3067\u3059\u3002\u30ad\u30e9\u30fc\uff34\u7d30\u80de\u306f\u9069\u5207\u306a\u4fe1\u53f7\u3092\u3082\u3089\u3046\u3068\u653b\u6483\u30e2\u30fc\u30c9\u306b\u306a\u308a\u307e\u3059\u3002\u4e0a\u8a18\u8a18\u4e8b\u306b\u3042\u308b\u3088\u3046\u306b\u3001CAR-T\u7d30\u80de\u306f\u304c\u3093\u7d30\u80de\u306e\u8868\u9762\u3092\u8a8d\u8b58\u3059\u308b\u6297\u4f53\u3068…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[42,46],"tags":[5,9],"class_list":["post-2148","post","type-post","status-publish","format-standard","hentry","category-tech","category-bio","tag-tech","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/2148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2148"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/2148\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}