T\u7d30\u80de\u306b\u3064\u3044\u3066\u306f\u6388\u696d\u3067\u7fd2\u3063\u3066\u3044\u308b\u3068\u601d\u3044\u307e\u3059\u304c\u3001\u5fa9\u7fd2\u3057\u3066\u304a\u304d\u307e\u3057\u3087\u3046\u3002
\n\u30fb\u5927\u304d\u3055\u306f2\u03bcm\u304f\u3089\u3044\u3002\u591a\u6570\u306e\u7a81\u8d77\u3092\u6301\u3064\u7403\u4f53\u3002\u4e0b\u8a18\u306e\u53f3\u306e\u9752\u3044\u3084\u3064\u3002
\n\u3000https:\/\/en.wikipedia.org\/wiki\/T_cell#\/media\/File:Red_White_Blood_cells.jpg
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\n\u30fbT\u306fthymus\uff08\u80f8\u817a\u3001\u767a\u97f3\u306f\u300c\u3055\u300d\u30a4\u30e0\u30b9\uff09\u306e\u7565\u3067\u3001\u80f8\u817a\u3067\u81ea\u4ed6\u8a8d\u8b58\u80fd\u3092\u6559\u80b2\uff08\u9078\u5225\uff09\u3055\u308c\u308b\u305f\u3081\u3001\u80f8\u817a\u306b\u5927\u91cf\u306b\u3044\u308b\u3053\u3068\u304c\u767a\u898b\u3055\u308c\u305f\u3053\u3068\u304b\u3089\u3002
\n\u30fbT\u7d30\u80de\u306e\u6297\u539f\u53d7\u5bb9\u4f53\uff08\u6297\u539f\u53d7\u5bb9\u4f53\u3001\u7570\u7269\u3092\u8a8d\u8b58\u3059\u308b\u30bb\u30f3\u30b5\u30fc\uff09\u306f\u6570\u767e\u4e07\u7a2e\u985e\u3042\u308a\u30011\u3064\u306eT\u7d30\u80de\u306f1\u7a2e\u985e\u3060\u3051\u306e\u6297\u539f\u53d7\u5bb9\u4f53\u309210\u4e07\u500b\u8868\u9762\u306b\u51fa\u3057\u3066\u3044\u308b\u3002
\n\u30fb\u6297\u539f\u53d7\u5bb9\u4f53\u306e\u591a\u69d8\u6027\u306f\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u304c\u81ea\u7136\u306b\u8d77\u3053\u308b\u305f\u3081\u300265\u00d727\u00d76\u00d740\u00d75=2106000\u7a2e\u985e\u3001\u3055\u3089\u306b\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u304c\u3042\u308b\u305d\u3046\u3067\u3059\u3002\u3053\u306e\u4ed5\u7d44\u307f\u306e\u767a\u898b\u8005\u306f\u5229\u6839\u5ddd\u535a\u58eb\u3002
\n\u3000https:\/\/www.kyowakirin.co.jp\/antibody\/basics\/diversity.html
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\n\u30fb\u30ad\u30e9\u30fcT\u7d30\u80de\u306e\u30bb\u30f3\u30b5\u30fc\u304c\u50cd\u304f\u3068\u653b\u6483\u304c\u958b\u59cb\u3055\u308c\u308b\uff08\u30df\u30b5\u30a4\u30eb\u767a\u5c04\u30dc\u30bf\u30f3\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3057\u3087\u3046\uff09\u3002\u30d1\u30fc\u30d5\u30a9\u30ea\u30f3\u3068\u30b0\u30e9\u30f3\u30b6\u30a4\u30e0\u3068\u3044\u3046\u7d30\u80de\u306b\u3068\u3063\u3066\u306f\u7206\u5f3e\u306e\u3088\u3046\u306a\u5206\u5b50\u3092\u51fa\u3059\u305d\u3046\u3067\u3059\u3002\u3053\u308c\u3089\u306f\u9762\u767d\u3044\u306e\u3067\u5f8c\u3067\u8a73\u7d30\u3092\u898b\u307e\u3057\u3087\u3046\u3002
\nhttps:\/\/en.wikipedia.org\/wiki\/Perforin-1
\nhttps:\/\/en.wikipedia.org\/wiki\/Granzyme
\n\u30fb\u653b\u6483\u505c\u6b62\u30dc\u30bf\u30f3\u3082\u3042\u308b\u3002\u304c\u3093\u7d30\u80de\u306f\u3053\u308c\u3092\u60aa\u7528\u3057\u307e\u3059\u3002<\/p>\n
\u60b2\u3057\u3044\u3053\u3068\u306b\u30a6\u30af\u30e9\u30a4\u30ca\u6226\u4e89\u3067\u6700\u8fd1\u767a\u9054\u3057\u3066\u3057\u307e\u3063\u305f\u653b\u6483\u30c9\u30ed\u30fc\u30f3\u306e\u3088\u3046\u306a\u3082\u306e\u3068\u601d\u3048\u3070\u3088\u3055\u305d\u3046\u3067\u3059\u306d\u3002\u73fe\u5728\u306e\u6280\u8853\u3067\u306f\u3053\u306e\u6a5f\u80fd\u3092 2\u03bcm\u3067\u4f5c\u308b\u306e\u306f\u7121\u7406\u3067\u3059\u3002\u767e\u500d\u306e\u5927\u304d\u3055\u306a\u3089\u3001\u9811\u5f35\u308c\u3070\u4f3c\u305f\u52d5\u304d\u306f\u3067\u304d\u305d\u3046\u306a\u6c17\u304c\u3057\u307e\u3059\u304c\u3001\u7206\u5f3e\u5206\u5b50\u306e\u5408\u6210\u6a5f\u80fd\u306f\u306a\u3044\u3067\u3059\u3002
\nCAR-T\uff08\u30ab\u30fc\u30fb\u30c6\u30a3\uff09\u7d30\u80de\u7642\u6cd5\u306f\u3001\u30ad\u30e9\u30fcT\u7d30\u80de\u306e\u653b\u6483\u958b\u59cb\u30dc\u30bf\u30f3\u3092\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u3067\u4f5c\u308a\u5909\u3048\u3001\u60a3\u8005\u306e\u304c\u3093\u7d30\u80de\u3092\u76f4\u63a5\u611f\u3058\u308b\u3088\u3046\u306b\u3057\u305f\u3082\u306e\u3092\u6570\u767e\u4e07\u500b\u306b\u5897\u3084\u3057\u3066\u70b9\u6ef4\u3059\u308b\u65b9\u6cd5\u3067\u3059\u3002\u8cbb\u7528\u304c\u6570\u5343\u4e07\u5186\u3059\u308b\u306e\u306f\u9ad8\u3059\u304e\u308b\u3068\u601d\u3044\u307e\u3059\u304c\u3001\u767e\u4e07\u5186\u4ee5\u4e0a\u304b\u304b\u308a\u305d\u3046\u306a\u3053\u3068\u306f\u60f3\u50cf\u304c\u3064\u304d\u307e\u3059\u3002\u4fa1\u683c\u304c\u4e0b\u304c\u308c\u3070\u9ad8\u984d\u533b\u7642\u8cbb\u306e\u554f\u984c\u306f\u304b\u306a\u308a\u8efd\u6e1b\u3055\u308c\u308b\u306e\u3067\u3001\u304b\u304b\u308f\u3063\u3066\u3044\u308b\u4f01\u696d\uff08\u65e5\u672c\u3082\u591a\u6570\u3042\u308a\u307e\u3059\uff09\u306e\u6d3b\u8e8d\u306b\u671f\u5f85\u3057\u305f\u3044\u3067\u3059\u3002<\/p>\n
\u82f1\u8a9e\u306f\u3000https:\/\/en.wikipedia.org\/wiki\/T_cell
\n\u201dT cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. \u201d
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\nadaptive immune response \u7372\u5f97\u514d\u75ab\u5fdc\u7b54
\n\u201dT cells are born from hematopoietic stem cells, found in the bone marrow. \u201d
\nhematopoietic stem cells \u9020\u8840\u5e79\u7d30\u80de
\nbone marrow \u9aa8\u9ac4
\n“One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ “killer” (cytotoxic) and CD4+ “helper” T cells….Regulatory T cells are yet another distinct population of T cells that provide the critical mechanism of tolerance, whereby immune cells are able to distinguish invading cells from “self”.”
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\nregulatory T cells \u5236\u5fa1T\u7d30\u80de
\nare yet another distinct population \u307e\u305f\u5225\u306e\u305d\u308c\u306a\u308a\u306e\u5272\u5408\u306e
\ndistinguish \u533a\u5225\u3059\u308b
\ninvading cells \u4fb5\u7565\u7d30\u80de<\/p>\n","protected":false},"excerpt":{"rendered":"
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