{"id":2087,"date":"2024-11-26T00:00:00","date_gmt":"2024-11-26T00:00:00","guid":{"rendered":"urn:uuid:4f44e3d8-c48d-402e-aff5-ca64303e4683"},"modified":"2024-11-26T00:00:00","modified_gmt":"2024-11-26T00:00:00","slug":"human-cell-atlasnozhong-shen","status":"publish","type":"post","link":"https:\/\/www.sekaiken.com\/?p=2087","title":{"rendered":"Human Cell Atlas\u306e\u4e2d\u8eab"},"content":{"rendered":"<p>Human Cell Atlas \u306e\u4e2d\u3092\u898b\u308b\u3068\u4f8b\u3048\u3070\u4e0b\u8a18\u306e\u30da\u30fc\u30b8\u304c\u80ba\u306e\u30c7\u30fc\u30bf\u3060\u305d\u3046\u3067\u3059\u3002\u9ed2\u3044 umap \u3068\u3044\u3046\u56f3\u5f62\u304c\u7d30\u80de\u306e\u7a2e\u985e\u3084\u5730\u57df\u6027\u5225\u306a\u3069\u306e\u30c1\u30a7\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u3092on\/off\u3059\u308b\u3068\u5909\u308f\u308a\u307e\u3059\u304c\u3001\u4f55\u3092\u793a\u3057\u3066\u3044\u308b\u56f3\u306a\u306e\u304b\u3001\u610f\u5473\u304c\u3088\u304f\u308f\u304b\u308a\u307e\u305b\u3093\u3002<br \/>\nhttps:\/\/cellxgene.cziscience.com\/e\/066943a2-fdac-4b29-b348-40cede398e4e.cxg\/<br \/>\n\u89e3\u8aac\u8a18\u4e8b\u3092\u8aad\u3093\u3067\u307f\u308b\u3053\u3068\u306b\u3057\u307e\u3057\u3087\u3046\u3002\u4e0b\u8a18\u306b\u306f\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u304cHuman Cell Atlas\u306b\u3069\u306e\u3088\u3046\u306b\u4f7f\u308f\u308c\u308b\u304b\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u3002<br \/>\nhttps:\/\/www.nature.com\/articles\/d41586-024-03762-y<br 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\/>\nhttps:\/\/github.com\/mcgilldinglab\/UNAGI<br \/>\nHuman Cell Atlas\u306f\u73fe\u5728\u4e00\u90e8\u306e\u81d3\u5668\u306e\u307f\u516c\u958b\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\uff11\uff5e2\u5e74\u5f8c\u306b\u306f\u6700\u521d\u306e\u4eba\u4f53\u7d30\u80de\u5730\u56f3\u304c\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30fc\u30c4\u30fc\u30eb\u3068\u4e00\u7dd2\u306b\u516c\u958b\u3055\u308c\u308b\u305d\u3046\u3067\u3059\u3002\u3053\u308c\u306f\u304a\u305d\u3089\u304f\u3001\u591c\u7a7a\u306e\u661f\u3068\u540c\u3058\u304f\u3089\u3044\u7d30\u304b\u304f\u3066\u9762\u767d\u3044\u3067\u3059\u3002\u30a2\u30de\u30c1\u30e5\u30a2\u5929\u6587\u5b66\u8005\u306e\u3088\u3046\u306a\u30a2\u30de\u30c1\u30e5\u30a2\u4eba\u4f53\u5b66\u8005\u304c\u51fa\u3066\u304f\u308b\u3068\u4e88\u60f3\u3057\u307e\u3059\u3002\u79c1\u3082\u6687\u306b\u306a\u3063\u305f\u3089\u3084\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p>\u82f1\u8a9e\u306f\u4e0a\u8a18\u8a18\u4e8b\u304b\u3089\u3002<br \/>\n&ldquo;Such tools make massive data sets accessible&rdquo;<br \/>\nmassive \u81a8\u5927\u306a<br \/>\n&ldquo;Single-cell technologies have shattered the fuzzy lenses through which researchers conventionally view biology.&rdquo;<br \/>\nshatter \u7c89\u3005\u306b\u3059\u308b<br \/>\nfuzzy lenses \u307c\u3084\u3051\u305f\u30ec\u30f3\u30ba<br \/>\n&ldquo;At the forefront of the design \u2014 and use \u2014 of single-cell technologies is the Human Cell Atlas (HCA), which aims to catalogue every cell type in people. Launched in 2016, the project has profiled hundreds of millions of single cells, resulted in about 440 published studies and led to dozens of wet-lab and computational procedures.&rdquo;<br \/>\nforefront \u6700\u524d\u7dda<br \/>\nlaunched in 2016 2016\u5e74\u306b\u7acb\u3061\u4e0a\u3052\u3089\u308c\u305f<br \/>\nwet-lab and computational procedures \u30d7\u30ed\u300c\u30b9\u30a3\u300d\u30fc\u30b8\u30e3\u2015\u3000\u6c34\u3092\u4f7f\u3046\u5b9f\u9a13\u5ba4\u3068\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u306e\u624b\u9806<br \/>\n\u201d Available on the website GitHub, these computational tools include ways to catalogue cells and search atlas data; shortcuts for researchers to obtain spatial or multi-modal data at low cost; and in silico models that describe how cells interact and where and how diseased cells might respond to treatment.\u201d<br \/>\nGitHub \u30ae\u30c3\u30c8\u30cf\u30d6\u3000\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u7121\u6599\u3067\u516c\u958b\u3059\u308bweb\u30b5\u30a4\u30c8\u3002Git\u306f\u30d0\u30fc\u30b8\u30e7\u30f3\u7ba1\u7406\u306e\u30c4\u30fc\u30eb\u3002<br \/>\nshortcuts \u8fd1\u9053<br \/>\nspatial \u7a7a\u9593\u7684<br \/>\nmulti-modal \u8907\u6570\u306e\u7570\u306a\u308b\u30c7\u30fc\u30bf\u306e<br \/>\nin silico \u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u306e\u4e2d\u3067<br \/>\nhow diseased cells might respond to treatment \u75c5\u6c17\u306b\u306a\u3063\u305f\u7d30\u80de\u304c\u6cbb\u7642\u306b\u3069\u306e\u3088\u3046\u306b\u5fdc\u7b54\u3059\u308b\u304b<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Human Cell Atlas \u306e\u4e2d\u3092\u898b\u308b\u3068\u4f8b\u3048\u3070\u4e0b\u8a18\u306e\u30da\u30fc\u30b8\u304c\u80ba\u306e\u30c7\u30fc\u30bf\u3060\u305d\u3046\u3067\u3059\u3002\u9ed2\u3044 umap \u3068\u3044\u3046\u56f3\u5f62\u304c\u7d30\u80de\u306e\u7a2e\u985e\u3084\u5730\u57df\u6027\u5225\u306a\u3069\u306e\u30c1\u30a7\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u3092on\/off\u3059\u308b\u3068\u5909\u308f\u308a\u307e\u3059\u304c\u3001\u4f55\u3092\u793a\u3057\u3066\u3044\u308b\u56f3\u306a\u306e\u304b\u3001\u610f\u5473\u304c\u3088\u304f\u308f\u304b\u308a\u307e\u305b\u3093\u3002 https:\/\/cellxgene.cziscience.com\/e\/066943a2-fdac-4b29-b348-40cede398e4e.cxg\/ \u89e3\u8aac\u8a18\u4e8b\u3092\u8aad\u3093\u3067\u307f\u308b\u3053\u3068\u306b\u3057\u307e\u3057\u3087\u3046\u3002\u4e0b\u8a18\u306b\u306f\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u304cHuman Cell Atlas\u306b\u3069\u306e\u3088\u3046\u306b\u4f7f\u308f\u308c\u308b\u304b\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u3002 https:\/\/www.nature.com\/articles\/d415&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[42,46],"tags":[5,9],"class_list":["post-2087","post","type-post","status-publish","format-standard","hentry","category-tech","category-bio","tag-tech","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/2087","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2087"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/2087\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2087"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2087"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2087"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}