{"id":2056,"date":"2024-10-14T00:00:00","date_gmt":"2024-10-14T00:00:00","guid":{"rendered":"urn:uuid:7e6e63d1-3df9-42b1-9010-399471aa3af9"},"modified":"2024-10-14T00:00:00","modified_gmt":"2024-10-14T00:00:00","slug":"shi-jie-noyan-jiu-suo-maikurornatetahesu","status":"publish","type":"post","link":"https:\/\/www.sekaiken.com\/?p=2056","title":{"rendered":"\u4e16\u754c\u306e\u7814\u7a76\u6240\uff1a\u30de\u30a4\u30af\u30edRNA\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9"},"content":{"rendered":"<p>\u3053\u30533\u5e74\u7a0b\u3001\u300c\u4eca\u65e5\u306e\u82f1\u8a9e\u300d\u3067\u3069\u3053\u3088\u308a\u3082\u901f\u3044\u30ce\u30fc\u30d9\u30eb\u8cde\u89e3\u8aac\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u4eca\u5e74\u306f\u90fd\u5408\u306b\u3088\u308a\u9045\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u7533\u3057\u8a33\u3042\u308a\u307e\u305b\u3093\u3002\u7269\u7406\u5b66\u8cde\u3068\u5316\u5b66\u8cde\u306e\uff21\uff29\u306e\u8a71\u306f\u3001\u79c1\u306e\u5927\u5b66\u9662\u96c6\u4e2d\u8b1b\u7fa9\u3067\u8a71\u3057\u3066\u3044\u307e\u3059\u306e\u3067\u305d\u308c\u306f\u307e\u305f\u306e\u6a5f\u4f1a\u306b\u3057\u3066\u3001\u4eca\u9031\u306f\u533b\u5b66\u751f\u7406\u5b66\u8cde\u306e\u30de\u30a4\u30af\u30edDNA(miRNA)\u306e\u8a71\u3092\u898b\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<br \/>\n\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u304c\u3067\u304d\u3066\u3044\u307e\u3059\u306d\u3002\u82f1\u30de\u30f3\u30c1\u30a7\u30b9\u30bf\u30fc\u5927\u5b66\u306e\u7814\u7a76\u5ba4\u304c\u904b\u55b6\u3057\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002<br \/>\nhttps:\/\/www.mirbase.org\/<br \/>\n\u65e5\u672c\u8a9e\u89e3\u8aac\u3068\u3057\u3066\u306f<br \/>\nhttps:\/\/www.cosmobio.co.jp\/support\/technology\/a\/microrna.asp<br \/>\nhttps:\/\/ja.wikipedia.org\/wiki\/MiRNA<br \/>\n\u304c\u3042\u308a\u307e\u3059\u3002\u9577\u305520-25\u5869\u57fa\u5bfe\u306eRNA\u306e\u65ad\u7247\u3067\u3001mRNA(\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA)\u306b\u304f\u3063\u3064\u3044\u3066\u30bf\u30f3\u30d1\u30af\u8cea\u3078\u306e\u7ffb\u8a33\u3092\u963b\u5bb3\u3057\u305f\u308a\u4fc3\u9032\u3057\u305f\u308a\u3057\u3066\u5236\u5fa1\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u4ee5\u524d\u805e\u3044\u305f\u8a71\u3067\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u306b\u3088\u308b\u751f\u4f53\u53cd\u5fdc\u306f20\u5206\u304f\u3089\u3044\u304b\u304b\u308b\u305d\u3046\u3067\u3059\u3002\u30de\u30a4\u30af\u30edRNA\u306f\u305d\u306e\u521d\u671f\u6bb5\u968e\u3092\u5236\u5fa1\u3057\u3066\u3044\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<br \/>\n\uff11\u3064\u306e\u30de\u30a4\u30af\u30edRNA\u306f\u8907\u6570\u306emRNA\u306e\u5236\u5fa1\u306b\u304b\u304b\u308f\u3063\u3066\u304a\u308a\u3001\u9006\u306b\uff11\u3064\u306emRNA\u306f\u8907\u6570\u306e\u30de\u30a4\u30af\u30edRNA\u306b\u3088\u308a\u5236\u5fa1\u3055\u308c\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u3002<br \/>\nMicrosoft copilot \u306b\u805e\u3044\u3066\u307f\u305f\u3089\u3001\u3053\u308c\u307e\u3067\u306b50000\u4ee5\u4e0a\u306emiRNA\u304c\u898b\u3064\u304b\u3063\u3066\u304a\u308a\u3001\u4eba\u9593\u306b\u3064\u3044\u3066\u30821000\u3092\u8d85\u3048\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002<br \/>\nmiRNA\u306b\u3088\u308b\u81a8\u5927\u306a\u5236\u5fa1\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u306d\u3002\u30ac\u30f3\u3001\u5fc3\u81d3\u75c5\u3001\u30a2\u30eb\u4e2d\u306a\u3069\u591a\u304f\u306e\u75be\u75c5\u306b\u304b\u304b\u308f\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u6700\u8fd1\u5206\u304b\u3063\u305f\u306e\u3067\u3001\u4eca\u5e74\u306e\u30ce\u30fc\u30d9\u30eb\u8cde\u306b\u306a\u3063\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3057\u3087\u3046\u3002<br \/>\n\u4eca\u5f8c\u3053\u306e\u5236\u5fa1\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u69cb\u9020\u304c\u89e3\u304b\u308c\u308b\u3067\u3057\u3087\u3046\u304c\u3001\u4eba\u9593\u304c\u899a\u3048\u3089\u308c\u308b\u3088\u3046\u306a\u5358\u7d14\u306a\u69cb\u9020\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u4eba\u9593\u304c\u6cd5\u5247\u6027\u306a\u304f\u899a\u3048\u3089\u308c\u308b\u306e\u306f\u4e16\u754c\u53f2\u3084\u65e5\u672c\u53f2\u306e\u6559\u79d1\u66f8\uff0b\u53c2\u8003\u66f8\u304f\u3089\u3044\u306e\u91cf\u3067\u3001\u305d\u308c\u3082\u4eba\u9593\u7684\u306a\u7269\u8a9e\u304c\u306a\u3044\u3068\u7121\u7406\u3067\u3059\u3002\u305d\u308c\u306a\u3089\u5316\u5b66\u306f\uff1f\u3068\u8a00\u308f\u308c\u308b\u3068\u3001\u79c1\u306b\u306f\u6cd5\u5247\u3082\u7269\u8a9e\u3082\u3042\u308b\u3088\u3046\u306b\u601d\u3048\u307e\u3059\u304c\u3001\u91cf\u306f\u3082\u3063\u3068\u591a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u306d\u3002miRNA\u306b\u3088\u308b\u5236\u5fa1\u7cfb\u306e\u69cb\u9020\u306f\u305d\u308c\u3089\u3088\u308a\u3082\u305a\u3063\u3068\u7121\u5473\u4e7e\u71e5\u3067\u3001\u91cf\u304c\u3072\u305f\u3059\u3089\u591a\u3044\u3082\u306e\u3060\u3068\u60f3\u50cf\u3057\u307e\u3059\u3002\u8a9e\u5b66\u306b\u5bfe\u5fdc\u3059\u308b\u8a18\u61b6\u91cf\u304f\u3089\u3044\u304b\u3082\u77e5\u308c\u307e\u305b\u3093\u3002<br \/>\n\u4f7f\u3044\u65b9\u3068\u3057\u3066\u306f\u3001\u5404miRNA\u306e\u8840\u4e2d\u3084\u7d44\u7e54\u6db2\u4e2d\u306e\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3057\u3066AI\u306b\u3069\u3046\u3059\u308c\u3070\u3044\u3044\u304b\u805e\u304f\u3053\u3068\u306b\u306a\u308b\u3067\u3057\u3087\u3046\u3002\u5f53\u7136miRNA\u81ea\u8eab\u3082\u85ac\u306b\u306a\u308b\u3067\u3057\u3087\u3046\u3057\u3001\u30b7\u30b9\u30c6\u30e0\u3068\u3057\u3066\u306e\u5206\u5b50\u304b\u88c5\u7f6e\uff08A\u3068B\u304c\u4e21\u65b9\u51fa\u3066\u3044\u305f\u3089C\u3092\u653e\u51fa\u3059\u308b\u3001\u306a\u3069\u3001\u7d44\u7e54\u5185\u306b\u57cb\u3081\u8fbc\u3080\u8d85\u5c0f\u578b\u88c5\u7f6e\uff1f\uff1f\uff09\u3082\u6709\u52b9\u3060\u3068\u601d\u3044\u307e\u3059\u3002\u30c7\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3\u30b9\u306e\u5fdc\u7528\u3068\u3057\u3066\u9762\u767d\u3044\u30d3\u30b8\u30cd\u30b9\u304c\u3067\u304d\u305d\u3046\u306b\u601d\u3044\u307e\u3059\u304c\u3001\u5de8\u5927AI\u4f01\u696d\u3092\u306f\u3058\u3081\u3068\u3057\u3066\u3001\u3059\u3067\u306b\u3044\u308d\u3044\u308d\u8003\u3048\u3066\u3044\u308b\u3067\u3057\u3087\u3046\u306d\u3002\u539f\u56e0\u4e0d\u660e\u306e\u96e3\u75c5\u306e\u3044\u304f\u3064\u304b\u306b\u3082miRNA\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u95a2\u308f\u3063\u3066\u3044\u308b\u3088\u3046\u306a\u4e88\u611f\u304c\u3057\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u8001\u5316\u304c\u6b62\u3081\u3089\u308c\u308b\u3068\u9762\u767d\u3044\u306e\u3067\u3059\u304c\u2026<\/p>\n<p>\u82f1\u8a9e\u306f https:\/\/www.nobelprize.org\/prizes\/medicine\/2024\/advanced-information\/ \u304b\u3089<br \/>\nThe Nobel prize in physiology or medicine \u30ce\u30fc\u30d9\u30eb\u533b\u5b66\u751f\u7406\u5b66\u8cde<br \/>\npost-transcriptional DNA\u7ffb\u8a33\u5f8c\u306e<br \/>\ngene regulation \u907a\u4f1d\u5b50\u5236\u5fa1<br \/>\nevolution \u9032\u5316<br \/>\nC. elegance \u7dda\u866b\u306e\u4e00\u7a2e\u3067\u3001\u5206\u5b50\u751f\u7269\u5b66\u306e\u7814\u7a76\u3067\u3088\u304f\u4f7f\u308f\u308c\u308b\u3000\uff08\u571f\u306e\u4e2d\u306b\u3044\u308b1mm\u304f\u3089\u3044\u306e\u5c0f\u3055\u3044\u3072\u3082\u72b6\u306e\u751f\u7269\uff09https:\/\/ja.wikipedia.org\/wiki\/%E7%B7%9A%E5%BD%A2%E5%8B%95%E7%89%A9<br \/>\nnematode \u300c\u30cd\u300d\u30de\u30c8\u30fc\u30c9\u3000\u7dda\u866b<br \/>\n\u201dThe discovery by Ambros and Ruvkun was completely unexpected and unveiled an evolutionarily conserved post-transcriptional regulatory mechanism mediated by microRNAs, with critical roles in animal development and for adult tissue function.\u201d<br \/>\nunveil \u30f4\u30a7\u30fc\u30eb\u3092\u5265\u304c\u3059\u3001\u660e\u3089\u304b\u306b\u3059\u308b<br \/>\ndevelopment \u767a\u9054\u3000\uff08\u3053\u306e\u5834\u5408\u306f\u5e7c\u4f53\u304c\u5927\u4eba\u306b\u306a\u308b\u3053\u3068\uff09<br \/>\ntissue \u7d44\u7e54<br \/>\n\u201dThe next breakthrough came when the Ruvkun lab found that the let-7 gene, unlike lin-4, was evolutionarily conserved across a wide range of animals. \u201d<br \/>\nconserved \u4fdd\u5b58\u3055\u308c\u308b<br \/>\nacross a wide range of animals \u591a\u304f\u306e\u52d5\u7269\u306b\u6e21\u3063\u3066 \u3000\u203b \u3053\u306eacross\u306f\u81ea\u7136\u306b\u4f7f\u3048\u308b\u3088\u3046\u306b\u3057\u305f\u3044\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3053\u30533\u5e74\u7a0b\u3001\u300c\u4eca\u65e5\u306e\u82f1\u8a9e\u300d\u3067\u3069\u3053\u3088\u308a\u3082\u901f\u3044\u30ce\u30fc\u30d9\u30eb\u8cde\u89e3\u8aac\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u4eca\u5e74\u306f\u90fd\u5408\u306b\u3088\u308a\u9045\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u7533\u3057\u8a33\u3042\u308a\u307e\u305b\u3093\u3002\u7269\u7406\u5b66\u8cde\u3068\u5316\u5b66\u8cde\u306e\uff21\uff29\u306e\u8a71\u306f\u3001\u79c1\u306e\u5927\u5b66\u9662\u96c6\u4e2d\u8b1b\u7fa9\u3067\u8a71\u3057\u3066\u3044\u307e\u3059\u306e\u3067\u305d\u308c\u306f\u307e\u305f\u306e\u6a5f\u4f1a\u306b\u3057\u3066\u3001\u4eca\u9031\u306f\u533b\u5b66\u751f\u7406\u5b66\u8cde\u306e\u30de\u30a4\u30af\u30edDNA(miRNA)\u306e\u8a71\u3092\u898b\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002 \u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u304c\u3067\u304d\u3066\u3044\u307e\u3059\u306d\u3002\u82f1\u30de\u30f3\u30c1\u30a7\u30b9\u30bf\u30fc\u5927\u5b66\u306e\u7814\u7a76\u5ba4\u304c\u904b\u55b6\u3057\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002 https:\/\/www.mirbase.org\/ \u65e5\u672c\u8a9e\u89e3\u8aac\u3068\u3057\u3066\u306f https:\/\/www.cosmobio.co.jp\/support\/technology\/a\/microrna.asp https:\/\/ja.wikip&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[47,46],"tags":[10,9],"class_list":["post-2056","post","type-post","status-publish","format-standard","hentry","category-worldresearchinstitutes","category-bio","tag-worldresearchinstitutes","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/2056","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2056"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/2056\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2056"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2056"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2056"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}