{"id":1888,"date":"2024-02-01T00:00:00","date_gmt":"2024-02-01T00:00:00","guid":{"rendered":"urn:uuid:bb68714e-bb09-4c2f-9bc4-5c54c8f6e86b"},"modified":"2024-02-01T00:00:00","modified_gmt":"2024-02-01T00:00:00","slug":"liu-huang-suan-hua-huan-yuan-xiao-su-sor-hazhong-kong-noqiu-ti","status":"publish","type":"post","link":"https:\/\/www.sekaiken.com\/?p=1888","title":{"rendered":"\u786b\u9ec4\u9178\u5316\u9084\u5143\u9175\u7d20\uff08SOR\uff09\u306f\u4e2d\u7a7a\u306e\u7403\u4f53"},"content":{"rendered":"<p>\u786b\u9ec4\u3092\u9178\u5316\u9084\u5143\u3059\u308b\u9175\u7d20 SOR(sulfur oxygenase reductase)\u306f\u9762\u767d\u3044\u5f62\u3092\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\nhttps:\/\/www.rcsb.org\/structure\/7X9W<br \/>\n\u4e2d\u7a7a\u306e\u7403\u4f53\u3067\u3059\u3002\u3053\u3093\u306a\u306e\u304c\u6307\u5148\u306e\u64cd\u4f5c\u3067\u898b\u3048\u308b\u306e\u3067\u3059\u304b\u3089\u3001\u3044\u3044\u6642\u4ee3\u3067\u3059\u30024\u56de\u5bfe\u79f0\u6027\u30683\u56de\u5bfe\u79f0\u6027\u304c\u3042\u3063\u3066\u3001\u51fa\u53e3\u306e\u3088\u3046\u306a\u3082\u306e\u304c\u3044\u304f\u3064\u304b\u958b\u3044\u3066\u3044\u307e\u3059\u3002\u304d\u308c\u3044\u3067\u3059\u3002<br \/>\nhttps:\/\/www.rcsb.org\/3d-view\/7X9W\/1<br \/>\n\u4f7f\u3063\u3066\u3044\u308b\u91d1\u5c5e\u30a4\u30aa\u30f3\u306f Fe3+\u306e\u3088\u3046\u3067\u3059\u3002<br \/>\nhttps:\/\/www.rcsb.org\/3d-view\/7X9W?preset=ligandInteraction&#038;label_asym_id=BA&#038;density=true<br \/>\n\u64cd\u4f5c\u3059\u308b\u76f8\u624b\u306f\u3000HSSCH2CH(NH2)COOH \u3060\u305d\u3046\u3067\u3059\u3002S-S\u3092\u5207\u3063\u3066H2S\u3092\u4f5c\u3063\u305f\u308a\u3001SO3^2-\u3092\u4f5c\u308b\u306e\u3060\u3068\u601d\u3044\u307e\u3059\u3002\u4e2d\u6027\u306eS8\u304b\u3089\u3069\u3046\u3084\u3063\u3066S\u3092\u53d6\u308a\u51fa\u3059\u306e\u304b\u306f\u898b\u3064\u304b\u308a\u307e\u305b\u3093\u3002<br \/>\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1133771\/<br \/>\n\u306b\u4ed5\u7d44\u307f\u306b\u3064\u3044\u3066\u5c11\u3057\u8a18\u8ff0\u304c\u3042\u308a\u307e\u3059(2004\u5e74\u306e\u8ad6\u6587)\u3002\u5b9f\u9a13\u306f\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u306e\u307b\u304b\u3001EDTA\u3067\u51e6\u7406\u3057\u3066Fe\u304c\u5916\u308c\u308b\u304b\u3069\u3046\u304b\u8abf\u3079\u305f\u308a\u3001\u4ed6\u306e\u30a4\u30aa\u30f3\u3092\u52a0\u3048\u305f\u308a\u3001\u5c3f\u7d20\u3092\u52a0\u3048\u3066\u5909\u6210\u3055\u305b\u305f\u308a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u306a\u305c\u4e2d\u7a7a\u306a\u306e\u304b\u3001\u4e0d\u601d\u8b70\u3067\u3059\u3002ferritin\uff08\u30d5\u30a7\u30ea\u30c1\u30f3\uff09\u3068\u3044\u3046\u9244\u3092\u305f\u3081\u8fbc\u3080\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u4f3c\u3066\u3044\u308b\u304c\u3082\u3063\u3068\u5927\u304d\u3044\u3068\u3044\u3046\u30b3\u30e1\u30f3\u30c8\u304c\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u3002\u9032\u5316\u4e0a\u3069\u3046\u95a2\u4fc2\u3057\u3066\u3044\u308b\u304b\u8208\u5473\u6df1\u3044\u3067\u3059\u3002\u89e3\u3051\u306a\u3044\u8b0e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p>\u203b\u5e74\u5ea6\u672b\u884c\u4e8b\u3067\u6642\u9593\u304c\u53d6\u308c\u305a\u3001S8\u306e\u5206\u89e3\u3084C-S\u7d50\u5408\u751f\u6210\u5207\u65ad\u306e\u79d8\u5bc6\u306b\u306f\u8e0f\u307f\u8fbc\u3081\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u307e\u305f\u3053\u306e\u30c6\u30fc\u30de\u3092\u8abf\u3079\u305f\u3044\u3067\u3059\u3002<\/p>\n<p>\u82f1\u8a9e\u306f https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1133771\/ \u304b\u3089\u3002<br \/>\n&ldquo;Wild-type, recombinant and refolded SOR possessed indistinguishable properties. &rdquo;<br \/>\nwild-type \u91ce\u751f\u578b\u3000\uff08\u81ea\u7136\u754c\u304b\u3089\u3068\u3063\u3066\u304d\u305f\u3082\u306e\uff09<br \/>\nrecombinant \u30d0\u30e9\u30d0\u30e9\u306b\u3057\u305f\u9175\u7d20\u306e\u30e6\u30cb\u30c3\u30c8\u3092\u518d\u7d50\u5408\u3057\u305f\u3082\u306e<br \/>\nrefolded \u5909\u6210\u3055\u305b\u305f\u3082\u306e\u3092\u3082\u3068\u306b\u6298\u308a\u305f\u305f\u3093\u3060\u30bf\u30f3\u30d1\u30af\u8cea<br \/>\npossess \u30dd\u300c\u30bc\u300d\u30b9\u3000\u6240\u6709\u3059\u308b<br \/>\nindistinguishable \u30a4\u30f3\u30c7\u30a3\u30b9\u300c\u30c6\u30a3\u300d\u30f3\u30b0\u30a3\u30c3\u30b7\u30e3\u3076\u30eb\u3000\u533a\u5225\u3067\u304d\u306a\u3044<br \/>\n&ldquo;The analysis of the quaternary structures showed a ball-shaped assembly with a central hollow core probably consisting of 24 subunits in a 432 symmetry.&rdquo;<br \/>\nquaternary \u30af\u300c\u30ef\u300d\u30fc\u30bf\u30ca\u30ea\u3000\uff14\u3064\u304b\u3089\u3067\u304d\u3066\u3044\u308b\uff08\u56db\u5143\u306e\uff09<br \/>\ncf. unitary \u5358\u5143\u306e\u3001binary \u4e8c\u5143\u306e\u3001 ternary\u3000\u4e09\u5143\u306e\u3001quinternary \u4e94\u5143\u306e\u3000\u3000\u3053\u308c\u3089\u306f\u30e9\u30c6\u30f3\u8a9e\u7531\u6765\u3067\u3057\u3087\u3046\u3002<br \/>\nhollow core \u4e2d\u7a7a\u306e\u82af<br \/>\n&ldquo;The spectroscopic data and the sequence comparison led to the proposal that the Acidianus ambivalens SOR typifies a new type of non-haem iron enzyme containing a mononuclear iron centre co-ordinated by carboxylate and\/or histidine ligands.&rdquo;<br \/>\n\u203b\u6301\u3063\u3066\u56de\u3063\u305f\u8a00\u3044\u56de\u3057\u3067\u3059\u304c\u3001\u8ad6\u6587\u306a\u3089\u8a31\u3055\u308c\u308b\u306e\u3067\u3057\u3087\u3046\u3002<br \/>\ntypify \u30c6\u30a3\u30d4\u30d5\u30a1\u30a4\u3000\u5178\u578b\u4f8b\u3068\u306a\u308b\u3002<br \/>\nnon-haem iron \u975e\u30d8\u30e0\u9244\u3000\u3000hemoglobin \u30d8\u30e2\u30b0\u30ed\u30d3\u30f3<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u786b\u9ec4\u3092\u9178\u5316\u9084\u5143\u3059\u308b\u9175\u7d20 SOR(sulfur oxygenase reductase)\u306f\u9762\u767d\u3044\u5f62\u3092\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/www.rcsb.org\/structure\/7X9W \u4e2d\u7a7a\u306e\u7403\u4f53\u3067\u3059\u3002\u3053\u3093\u306a\u306e\u304c\u6307\u5148\u306e\u64cd\u4f5c\u3067\u898b\u3048\u308b\u306e\u3067\u3059\u304b\u3089\u3001\u3044\u3044\u6642\u4ee3\u3067\u3059\u30024\u56de\u5bfe\u79f0\u6027\u30683\u56de\u5bfe\u79f0\u6027\u304c\u3042\u3063\u3066\u3001\u51fa\u53e3\u306e\u3088\u3046\u306a\u3082\u306e\u304c\u3044\u304f\u3064\u304b\u958b\u3044\u3066\u3044\u307e\u3059\u3002\u304d\u308c\u3044\u3067\u3059\u3002 https:\/\/www.rcsb.org\/3d-view\/7X9W\/1 \u4f7f\u3063\u3066\u3044\u308b\u91d1\u5c5e\u30a4\u30aa\u30f3\u306f Fe3+\u306e\u3088\u3046\u3067\u3059\u3002 https:\/\/www.rcsb.org\/3d-view\/7X9W?preset=ligandInteraction&#038;label_a&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,46],"tags":[7,9],"class_list":["post-1888","post","type-post","status-publish","format-standard","hentry","category-materials","category-bio","tag-materials","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1888","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1888"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1888\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1888"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1888"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1888"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}