\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u3067\u306f\u3001\u521d\u671f\u3067\u306f10\u212b\u3001\u73fe\u5728\u306f2\u212b\u4ee5\u4e0b\u306e\u5206\u89e3\u80fd\u30673\u6b21\u5143\u306e\u50cf\u304c\u5f97\u3089\u308c\u307e\u3059\u304c\u3001\u539f\u5b50\u3088\u308a\u306f\u5927\u304d\u3044\u306e\u3067\u3001\u305d\u3053\u306b\u4f55\u306e\u539f\u5b50\u304c\u3042\u308b\u304b\u3068\u3044\u3046\u3053\u3068\u306f\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u3068\u4eba\u9593\u306b\u3088\u308b\u63a8\u6e2c\u306b\u306a\u308a\u307e\u3059\u3002
\n\u751f\u4f53\u5206\u5b50\u3067\u91cd\u8981\u306a\u70ad\u7d20\u3001\u7a92\u7d20\u3001\u9178\u7d20\u306f\u539f\u5b50\u756a\u53f7\u304c\u8fd1\u3044\u306e\u3067\u3001\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u3067\u533a\u5225\u3059\u308b\u306e\u306f\u305f\u3044\u3078\u3093\u3067\u3059\u3002\u4e00\u65b9\u3001\u5358\u7d50\u6676X\u7dda\u56de\u6298\u3067\u306f\u5206\u89e3\u80fd\u304c\u539f\u5b50\u3088\u308a\u3082\u5c0f\u3055\u3044\u306e\u3067\uff08\u56de\u6298\u50cf\u306e\u4f4d\u76f8\u554f\u984c\u304c\u3042\u308b\u306e\u3067\u307e\u305f\u5225\u7a2e\u306e\u554f\u984c\u304c\u3042\u308a\u307e\u3059\u304c\uff09\u539f\u5b50\u7a2e\u306e\u533a\u5225\u306f\u307b\u307c\u81ea\u52d5\u3067\u3067\u304d\u308b\u306e\u3067\u3001\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u3088\u308a\u306f\u4fe1\u983c\u6027\u304c\u3042\u308a\u307e\u3059\u3002
\n\u305d\u3053\u3067\u3001\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u3067\u306f\u5206\u5b50\u306e\u4e00\u6b21\u69cb\u9020\uff08\u30a2\u30df\u30ce\u9178\u3084\u6838\u9178\u5869\u57fa\u306e\u914d\u5217\uff09\u306e\u60c5\u5831\u3082\u4f7f\u3063\u3066\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u306b\u63a8\u6e2c\u3055\u305b\u308b\u65b9\u6cd5\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n\u305d\u306e\u7d50\u679c\u3001\u304d\u308c\u3044\u306a\u539f\u5b50\u50cf\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u300c\u4eca\u6708\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u300d\u306b\u9078\u3070\u308c\u305f\u4e0b\u8a18\u306f\u3001\u690d\u7269\u306e\u514d\u75ab\u306b\u304b\u304b\u308f\u308b\u3082\u306e\u3060\u305d\u3046\u3067\u3059\u304c\u3001\u53f3\u5074\u306e”style”\u3092”licorice”\u306b\u3059\u308b\u3068\u539f\u5b50\u3092\u898b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002
\nhttps:\/\/www.rcsb.org\/3d-view\/ngl\/6j5t
\n\u3053\u308c\u3082\u4e00\u7a2e\u306eAI\u3068\u3082\u8a00\u3048\u307e\u3059\u306d\u3002\u9ad8\u5ea6\u306a\u6280\u8853\u3067\u3059\u3002\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u306f1\u53f0\u6570\u5104\u5186\uff08\u304a\u305d\u3089\u304f\u5f8c\u534a\uff09\u3068\u306e\u3053\u3068\u3067\u3059\u304c\u3001\u5165\u672d\u60c5\u5831\u3092\u898b\u308b\u30682020\u5e74\u3053\u308d\u304b\u3089\u305f\u304f\u3055\u3093\u58f2\u308c\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u306e\u4fa1\u5024\u3082\u9ad8\u305d\u3046\u3067\u3059\u3002\u7121\u6a5f\u7269\u306b\u3082\u540c\u69d8\u306e\u65b9\u6cd5\u304c\u4f7f\u3048\u308b\u88c5\u7f6e\u304c\u3067\u304d\u3066\u3044\u307e\u3059\u304c\uff08\u5206\u89e3\u80fd\u306f\u305a\u3063\u3068\u4f4e\u304f\u3066\u826f\u3044\uff09\u3001\u5024\u6bb5\u306f\u6570\u5104\u5186\uff08\u524d\u534a\uff09\u3067\u3059\u3002
\n\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u4e0b\u8a18\u306b\u8a73\u3057\u3044\u3067\u3059\u3002
\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2409374\/
\nhttps:\/\/www.sciencedirect.com\/science\/article\/pii\/S0079610720300699
\n\u3057\u304b\u3057\u3001\u9593\u9055\u3044\u3082\u3042\u308b\u307f\u305f\u3044\u3067\u3001\u4e0b\u8a18\u306b\u8907\u6570\u306e\uff13\u6b21\u5143\u96fb\u9855\u50cf\u3092\u6bd4\u8f03\u3057\u3066\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u539f\u5b50\u69cb\u9020\u3092\u5f97\u308b\u65b9\u6cd5\u304c\u89e3\u8aac\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/pubs.acs.org\/doi\/10.1021\/acs.jcim.9b01103<\/p>\n
\u82f1\u8a9e\u306f\u3000https:\/\/pdb101.rcsb.org\/motm\/287\u3000\u304b\u3089\u3002
\n“Like humans and all other organisms, plants can become infected by pathogens and stricken with disease.”
\nplants \u690d\u7269
\nbecome infected by pathogens \u300c\u30d1\u300d\u305d\u30b8\u30a7\u30f3\u3000\u75c5\u539f\u4f53\u306b\u611f\u67d3\u3059\u308b
\nbecome stricken \u30b9\u30c8\u30ea\u30c3\u30b1\u30f3\u3000< strike \u30b9\u30c8\u30e9\u30a4\u30af\u3000\u8972\u308f\u308c\u308b
\n“However, unlike humans which have both adaptive and innate immunities, plants only have innate immunity.”
\n\u7372\u5f97\uff08\u9069\u5fdc\uff09\u514d\u75ab\u3068\u81ea\u7136\u514d\u75ab\u306e\u4e21\u65b9\u304c\u3042\u308b\u4eba\u985e\u3068\u9055\u3063\u3066\u690d\u7269\u306f\u81ea\u7136\u514d\u75ab\u3057\u304b\u306a\u3044\u3002
\nimmunity \u514d\u75ab
\nimmune \u30a4\u300c\u30df\u30e5\u300d\u30fc\u30f3\u3000\u514d\u75ab\u306e\u3000\uff5e\u306b\u514d\u75ab\u304c\u3042\u308b(be immune to)
\n“When this detection event occurs, it will trigger a cascade of events that ultimately lead to an immune response to fend off the pathogen and maintain survival. ”
\nfend off \u6255\u3044\u306e\u3051\u308b
\nmaintain survival \u3059\u3054\u3044\u8a00\u8449\u3067\u3059\u304c\u3001\u3000\u300c\u751f\u5b58\u3092\u7dad\u6301\u3059\u308b\u300d\u3068\u8a33\u3059\u3079\u304d\u3067\u3057\u3087\u3046\u304b\u3002
\n“Once inside the plant cell, AvrAC starts its attack by adding uridyl groups to regulatory kinase enzymes, which inhibits immune signaling pathways and thereby leads to increased virulence. Cleverly, however, the plant cell fights back by baiting it with a decoy protein called PBL2. When PBL2 is uridylylated, instead of shutting down the immune response, it begins the process of building the resistosome”
\n\u203bAvrAC\u306f\u75c5\u539f\u4f53\u3067\u3001\u5236\u5fa1\u9175\u7d20\u3092\u6539\u5909\uff08\u30a6\u30ea\u30b8\u30eb\u5316\uff09\u3059\u308b\u3053\u3068\u3067\u514d\u75ab\u4fe1\u53f7\u3092\u505c\u6b62\u3055\u305b\u308b\u306e\u3067\u3059\u304c\u3001\u690d\u7269\u5074\u306f\u304a\u3068\u308a(decoy)\u306ePBL2\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u7528\u610f\u3057\u3066\u3044\u3066\u3001\u305d\u308c\u304c\u6539\u5909\u3055\u308c\u308b\u3068\u3001resistosome\u3068\u3044\u3046\u56f3\u306b\u793a\u3055\u308c\u3066\u3044\u308b\u30d2\u30c8\u30c7\u307f\u305f\u3044\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4f5c\u3089\u308c\u3001\u81ea\u3089\u306e\u7d30\u80de\u819c\u306b\u4e2d\u592e\u90e8\u306e\u7a81\u8d77\u3067\u7a74\u3092\u3042\u3051\u3066\u81ea\u7206\u3059\u308b\u3053\u3068\u3067\u611f\u67d3\u3092\u9632\u304e\u307e\u3059\u3002
\nuridyl group \u30a6\u30ea\u30b8\u30eb\u57fa
\nbait \u990c\u3092\u4e0e\u3048\u308b
\nvirulence \u75c5\u6bd2\u6027
\ndecoy \u300c\u30c7\u300d\u30b3\u30a4\u3000\u304a\u3068\u308a<\/p>\n","protected":false},"excerpt":{"rendered":"
\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u3067\u306f\u3001\u521d\u671f\u3067\u306f10\u212b\u3001\u73fe\u5728\u306f2\u212b\u4ee5\u4e0b\u306e\u5206\u89e3\u80fd\u30673\u6b21\u5143\u306e\u50cf\u304c\u5f97\u3089\u308c\u307e\u3059\u304c\u3001\u539f\u5b50\u3088\u308a\u306f\u5927\u304d\u3044\u306e\u3067\u3001\u305d\u3053\u306b\u4f55\u306e\u539f\u5b50\u304c\u3042\u308b\u304b\u3068\u3044\u3046\u3053\u3068\u306f\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u3068\u4eba\u9593\u306b\u3088\u308b\u63a8\u6e2c\u306b\u306a\u308a\u307e\u3059\u3002 \u751f\u4f53\u5206\u5b50\u3067\u91cd\u8981\u306a\u70ad\u7d20\u3001\u7a92\u7d20\u3001\u9178\u7d20\u306f\u539f\u5b50\u756a\u53f7\u304c\u8fd1\u3044\u306e\u3067\u3001\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u3067\u533a\u5225\u3059\u308b\u306e\u306f\u305f\u3044\u3078\u3093\u3067\u3059\u3002\u4e00\u65b9\u3001\u5358\u7d50\u6676X\u7dda\u56de\u6298\u3067\u306f\u5206\u89e3\u80fd\u304c\u539f\u5b50\u3088\u308a\u3082\u5c0f\u3055\u3044\u306e\u3067\uff08\u56de\u6298\u50cf\u306e\u4f4d\u76f8\u554f\u984c\u304c\u3042\u308b\u306e\u3067\u307e\u305f\u5225\u7a2e\u306e\u554f\u984c\u304c\u3042\u308a\u307e\u3059\u304c\uff09\u539f\u5b50\u7a2e\u306e\u533a\u5225\u306f\u307b\u307c\u81ea\u52d5\u3067\u3067\u304d\u308b\u306e\u3067\u3001\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u3088\u308a\u306f\u4fe1\u983c\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u305d\u3053\u3067\u3001\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u3067\u306f\u5206\u5b50\u306e\u4e00\u6b21\u69cb\u9020\uff08\u30a2\u30df\u30ce\u9178\u3084\u6838\u9178\u5869\u57fa\u306e\u914d\u5217\uff09\u306e\u60c5\u5831\u3082\u4f7f\u3063\u3066\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u306b\u63a8\u6e2c\u3055\u305b\u308b\u65b9\u6cd5\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u305d\u306e\u7d50\u679c\u3001\u304d…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[42,44,46],"tags":[5,7,9],"class_list":["post-1828","post","type-post","status-publish","format-standard","hentry","category-tech","category-materials","category-bio","tag-tech","tag-materials","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1828","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1828"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1828\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1828"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1828"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1828"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}