2023\u5e74\u306e\u30ce\u30fc\u30d9\u30eb\u533b\u5b66\u751f\u7406\u5b66\u8cde\u306f\u3001mRNA\uff08\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff09\u30ef\u30af\u30c1\u30f3\u306e\u767a\u660e\u8005\u306b\u4e0e\u3048\u3089\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306b\u4f7f\u308f\u308c\u305f\u306e\u3067\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u306d\u3002\u7d30\u80de\u5185\u306bmRNA\u304c\u3046\u307e\u304f\u5165\u308b\u3068\u3001\u5bfe\u5fdc\u3057\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4f5c\u3089\u308c\u307e\u3059\u3002\u305d\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4f8b\u3048\u3070\u30b3\u30ed\u30ca\u30a6\u30a3\u30eb\u30b9\u306e\u8868\u9762\u7a81\u8d77\u306e\u3082\u306e\u3060\u3068\u3059\u308b\u3068\u3001\u751f\u4f53\u306e\u514d\u75ab\u53cd\u5fdc\u304c\u8a98\u8d77\u3055\u308c\u3001\u30a6\u30a3\u30eb\u30b9\u306e\u611f\u67d3\u3092\u521d\u671f\u306b\u6291\u3048\u8fbc\u3080\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u4ed5\u7d44\u307f\u306e\u8a73\u7d30\u306e\u89e3\u8aac\u306f\u4e0b\u8a18\u3067\u3059\uff08\u4eca\u56de\u53d7\u8cde\u306e Weissman\u6559\u6388\u304c\u8457\u8005\uff09\u3002
\nhttps:\/\/www.nature.com\/articles\/nrd.2017.243
\nmRNA\u30ef\u30af\u30c1\u30f3\u306e\u5229\u70b9\u3068\u3057\u3066\u3001(1)\u5b89\u5168\u6027\uff08\u75c5\u539f\u6027\u304c\u306a\u304f\u3001\u4f53\u5185\u306e\u534a\u6e1b\u671f\u3092\u8abf\u6574\u3082\u3067\u304d\u308b\uff09(2)\u52b9\u7387\u6027\uff08\u5b89\u5b9a\u6027\u3092\u5897\u3057\u3001\u591a\u304f\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u751f\u7523\u3067\u304d\u308b\u3088\u3046\u306b\u6539\u5909\u3067\u304d\u308b\uff09(3)\u751f\u7523\u6027\uff08\u751f\u7269\u3092\u4ecb\u3055\u306a\u3044\u3068\u4f5c\u308c\u306a\u3044\u30bf\u30f3\u30d1\u30af\u8cea\u305d\u306e\u3082\u306e\u3088\u308a\u3082\u3001\u6838\u9178\u914d\u5217\u5408\u6210\u88c5\u7f6e\u3067\u5408\u6210\u3067\u304d\u308b\u305f\u3081\u65e9\u304f\u751f\u7523\u3067\u304d\u308b\u30fb\u30fb\u30fb\u3053\u306e\u5229\u70b9\u306f\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306b\u751f\u304b\u3055\u308c\u307e\u3057\u305f\uff09\u3002
\n\u53cd\u30ef\u30af\u30c1\u30f3\u4e3b\u7fa9\u306e\u4e3b\u5f35\u3067\u4e0d\u5b89\u306b\u306a\u3089\u306a\u3044\u3088\u3046\u306b\u3001EU\u306f\u4e0b\u8a18\u306e\u3088\u3046\u306a\u30da\u30fc\u30b8\u3092\u4f5c\u3063\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/ec.europa.eu\/research-and-innovation\/en\/horizon-magazine\/five-things-you-need-know-about-mrna-vaccine-safety
\nDNA\u3092\u6539\u5909\u3059\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3001\u3068\u3044\u3046\u306e\u304c\u5f37\u8abf\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n\u4e0a\u8a18\u89e3\u8aac\u8ad6\u6587\u3067\u77e5\u308a\u307e\u3057\u305f\u304c\u3001\u5916\u6765\u306emRNA\u306b\u5bfe\u3057\u3066\u7d30\u80de\u5074\u306e\u9632\u5fa1\u6a5f\u69cb\uff08\u708e\u75c7\u767a\u751f\uff09\u304c\u50cd\u304b\u306a\u3044\u3088\u3046\u306b\u7cbe\u88fd\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3060\uff08\u7279\u306bmRNA\u304c\u4e8c\u672c\u9396\u306b\u306a\u308b\u4e0d\u7d14\u7269\u304c\u30c0\u30e1\uff09\u3068\u3044\u3046\u3053\u3068\u3092\u793a\u3057\u3001\u3055\u3089\u306bmRNA\u306e\u7aef\u306b\u304f\u3063\u3064\u3051\u3066\u708e\u75c7\u3092\u8d77\u3053\u3055\u305b\u305a\u306b\u52b9\u7387\u3088\u304f\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u3092\u4fc3\u3059\u914d\u5217\u3092\u5730\u9053\u306b\u958b\u767a\u3057\u305f\u306e\u304c\u3082\u3046\u4e00\u4eba\u306e\u53d7\u8cde\u8005\u306eKariko\u6559\u6388\u3067\u3001\u4e8c\u4eba\u306f\u5171\u540c\u7814\u7a76\u3057\u3066\u3044\u305f\u3088\u3046\u3067\u3059\u3002\u4e0b\u8a18\u304cNHK\u304c\u89e6\u308c\u3066\u3044\u308b2005\u5e74\u306e\u696d\u7e3e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3044\u307e\u3059\u3002
\nhttps:\/\/www.sciencedirect.com\/science\/article\/pii\/S1074761305002116
\n\u307e\u305f\u3001RNA\u306f\u7d30\u80de\u9593\u306b\u5206\u6ccc\u3055\u308c\u3066\u3044\u308bRNA\u5206\u89e3\u9175\u7d20\u3067\u3059\u3050\u5206\u89e3\u3055\u308c\u308b\u306e\u3067\u3001\u3084\u3089\u308c\u306a\u3044\u3088\u3046\u306b\u8102\u8cea\u4e8c\u91cd\u5c64\u30ab\u30d7\u30bb\u30eb\u306b\u304f\u308b\u3080\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u5b9f\u7528\u5316\u307e\u3067\u306b15\u5e74\u4ee5\u4e0a\u304b\u304b\u3063\u305f\u306e\u306f\u7d0d\u5f97\u3067\u3059\u3002mRNA\u3092\u30ac\u30f3\u306b\u3082\u4f7f\u304a\u3046\u3068\u3059\u308b\u7814\u7a76\u3082\u884c\u308f\u308c\u3066\u3044\u3066\u9032\u5c55\u3057\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002<\/p>\n
\u82f1\u8a9e\u306f\u3000https:\/\/penntoday.upenn.edu\/news\/katalin-kariko-and-drew-weissman-penns-historic-mrna-vaccine-research-team-win-2023-nobel\u3000\u304b\u3089
\ntherapeutic \u305b\u30e9\u30d4\u30e5\u30fc\u30c6\u30a3\u30c3\u30af\u3000\u6cbb\u7642\u306e
\nNobel prize in Physiology or Medicine \u30ce\u30fc\u30d9\u30eb\u533b\u5b66\u751f\u7406\u5b66\u8cde
\naffiliated with Penn \u30da\u30f3\u30b7\u30eb\u30d9\u30cb\u30a2\u5927\u5b66\u306b\u6240\u5c5e\u3059\u308b
\n“After a chance meeting while photocopying research papers” \u7814\u7a76\u8ad6\u6587\u3092\u30b3\u30d4\u30fc\u3057\u3066\u3044\u308b\u3068\u304d\u306e\u5076\u7136\u306e\u51fa\u4f1a\u3044\u306e\u5f8c
\n“The mRNA-based vaccines elicited a robust immune response.”
\nelicit\u3000\u5f15\u304d\u51fa\u3059\u3001\u8a98\u5f15\u3059\u308b\u3000level 9
\n“Unlike other vaccines, a live or attenuated virus is not injected or required at any point.”
\nattenuate \u30a2\u300c\u30c6\u300d\u30cb\u30e5\u30a8\u30a4\u30c8\u3000\u6e1b\u8870\u3055\u305b\u308b\u3001\u5f31\u6bd2\u5316\u3059\u308b\u3000attenuator \u3000\u30aa\u30fc\u30c7\u30a3\u30aa\u306e \u30a2\u30c3\u30c6\u30cd\u30fc\u30bf\u3067\u3059\u3002
\n“As companies worked to quickly develop and deploy vaccines…”
\n\u4f01\u696d\u305f\u3061\u304c\u30ef\u30af\u30c1\u30f3\u3092\u958b\u767a\u3057\u5c55\u958b\u3059\u308b\u305f\u3081\u306b\u50cd\u304f\u306b\u3064\u308c\u3066…
\ndeploy \u30c7\u30d7\u308d\u30a4\u3000\u3000\u5c55\u958b\u3059\u308b\u3001\u90e8\u968a\u3092\u914d\u7f6e\u3059\u308b level 9 <\/p>\n","protected":false},"excerpt":{"rendered":"
2023\u5e74\u306e\u30ce\u30fc\u30d9\u30eb\u533b\u5b66\u751f\u7406\u5b66\u8cde\u306f\u3001mRNA\uff08\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff09\u30ef\u30af\u30c1\u30f3\u306e\u767a\u660e\u8005\u306b\u4e0e\u3048\u3089\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306b\u4f7f\u308f\u308c\u305f\u306e\u3067\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u306d\u3002\u7d30\u80de\u5185\u306bmRNA\u304c\u3046\u307e\u304f\u5165\u308b\u3068\u3001\u5bfe\u5fdc\u3057\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4f5c\u3089\u308c\u307e\u3059\u3002\u305d\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4f8b\u3048\u3070\u30b3\u30ed\u30ca\u30a6\u30a3\u30eb\u30b9\u306e\u8868\u9762\u7a81\u8d77\u306e\u3082\u306e\u3060\u3068\u3059\u308b\u3068\u3001\u751f\u4f53\u306e\u514d\u75ab\u53cd\u5fdc\u304c\u8a98\u8d77\u3055\u308c\u3001\u30a6\u30a3\u30eb\u30b9\u306e\u611f\u67d3\u3092\u521d\u671f\u306b\u6291\u3048\u8fbc\u3080\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u4ed5\u7d44\u307f\u306e\u8a73\u7d30\u306e\u89e3\u8aac\u306f\u4e0b\u8a18\u3067\u3059\uff08\u4eca\u56de\u53d7\u8cde\u306e Weissman\u6559\u6388\u304c\u8457\u8005\uff09\u3002 https:\/\/www.nature.com\/articles\/nrd.2017.243 mRNA\u30ef\u30af\u30c1\u30f3\u306e\u5229\u70b9\u3068\u3057\u3066\u3001(1)\u5b89\u5168\u6027\uff08\u75c5\u539f\u6027\u304c\u306a\u304f\u3001\u4f53\u5185\u306e\u534a…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[42,46],"tags":[5,9],"class_list":["post-1806","post","type-post","status-publish","format-standard","hentry","category-tech","category-bio","tag-tech","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1806","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1806"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1806\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1806"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1806"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1806"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}