\u7d30\u80de\u5206\u88c2\u306e\u56de\u6570\u3092\u5236\u9650\u3059\u308bHayflick limit\uff08\u4eba\u9593\u306e\u4f53\u7d30\u80de\u306f\u7d0450\u56de\uff09\u306e\u4ed5\u7d44\u307f\u306f\u3001\u30c6\u30ed\u30e1\u30a2\u304c\u77ed\u304f\u306a\u308b\u3053\u3068\u3067\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30c6\u30ed\u30e1\u30a2\u306f\u54fa\u4e73\u985e\u3067\u306f(TTAGGG)\u304c\u591a\u6570\u7e70\u308a\u8fd4\u3055\u308c\u305f\u914d\u5217\u304cDNA\u306e\u7aef\u306b\u304f\u3063\u3064\u3044\u3066\u3044\u308b\u3082\u306e\u3067\u3001\u67d3\u8272\u4f53\u3068\u3057\u3066\u307e\u3068\u307e\u308b\u6642\u306e\u672b\u7aef\u306e\u4fdd\u8b77\u306b\u5f79\u7acb\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4e0b\u8a18wikipedia\u306b\u308f\u304b\u308a\u3084\u3059\u3044\u5199\u771f\u304c\u3067\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/en.wikipedia.org\/wiki\/Telomere
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\n\u57f9\u990a\u7d30\u80de\u5206\u88c2\u304c\u6700\u5927\u56de\u6570\u307e\u3067\u8d77\u3053\u3063\u305f\u5f8c\u306e\u72b6\u614b\u3092\u300c\u7d30\u80de\u8001\u5316\u300d\u3068\u3044\u3046\u305d\u3046\u3067\u3059\u304c\u3001\u751f\u7269\u4f53\u5168\u4f53\u306e\u8001\u5316\u3068\u4e00\u81f4\u3057\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3001wikipedia\u306a\u3069\u306f\u5965\u6b6f\u306b\u3082\u306e\u304c\u631f\u307e\u3063\u305f\u3088\u3046\u306a\u66f8\u304d\u65b9\u3092\u3057\u3066\u3044\u307e\u3059\u3002\u3044\u308d\u3044\u308d\u8aad\u307f\u307e\u3057\u305f\u304c\u3001\u5f37\u304f\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u306e\u306f\u5b9a\u8aac\u3068\u3044\u3063\u3066\u3088\u3044\u3068\u601d\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30c6\u30ed\u30e1\u30a2\u304c\u5206\u88c2\u306e\u305f\u3073\u306b\u77ed\u304f\u306a\u3063\u3066\u3044\u3063\u3066\u3001\u4f53\u7d30\u80de\u3067\u306f\u30c6\u30ed\u30e1\u30a2\u2015\u305c\u304c\u50cd\u304b\u306a\u3044\u3001\u3068\u3044\u3046\u73fe\u8c61\u304c\u3001Hayflick limit\u306e\u4ed5\u7d44\u307f\u3067\u3042\u308b\u3001\u3068\u3044\u3046\u306e\u3082\u5b9a\u8aac\u3067\u3059\u3002
\n\u305d\u3046\u3059\u308b\u3068\u3001(1)\u30c6\u30ed\u30e1\u30a2\u306e\u9577\u3055\u3092\u6e2c\u308c\u3070\u5bff\u547d\u304c\u4e88\u6e2c\u3067\u304d\u308b\u3001\u3068\u304b\u3001(2)\u30c6\u30ed\u30e1\u30a2\u2015\u305c\u3092\u4f53\u7d30\u80de\u3067\u767a\u73fe\u3055\u305b\u308c\u3070\u8001\u5316\u3092\u9006\u8ee2\u3067\u304d\u308b\u3001\u3068\u304b\u8003\u3048\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u5b9f\u969b\u305d\u308c\u306fweb\u691c\u7d22\u3059\u308b\u3068\u305f\u304f\u3055\u3093\u898b\u3064\u304b\u308a\u307e\u3059\u304c\u3001\u304b\u306a\u308a\u602a\u3057\u3044\u30d3\u30b8\u30cd\u30b9\u304c\u591a\u3044\u3067\u3059\u3002(1)\u306f\u3001\u6e2c\u5b9a\u30ad\u30c3\u30c8\u304c$100~$400\u3067\u58f2\u3063\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u304c\u3001\u540c\u3058\u500b\u4f53\u3067\u3082\u7d30\u80de\u306e\u7a2e\u985e\u306b\u3088\u3063\u3066\u307e\u3061\u307e\u3061\u306a\u306e\u3067\u3001\u7d30\u80de\u3092\u7279\u5b9a\u3057\u3066\u7cbe\u5ea6\u3088\u304f\u6e2c\u3089\u306a\u3044\u3068\u4f55\u3082\u308f\u304b\u3089\u306a\u3044\u305d\u3046\u3067\u3059\u3002\u300c\u98df\u4e8b\u306b\u3088\u308b\u30c6\u30ed\u30e1\u30a2\u5024\u306e\u5909\u5316\u306e\u6e2c\u5b9a\u300d\u3068\u3044\u3046\u6587\u732e\u304c\u3042\u308a\u3001\u300c\u3068\u3093\u3067\u3082\u300d\u306a\u5185\u5bb9\u3060\u3063\u305f\u306e\u3067\u9a5a\u304d\u307e\u3057\u305f\u3002(2)\u306f\u3001\u304c\u3093\u7d30\u80de\u306f\u304b\u306a\u308a\u306e\u5272\u5408\u3067\u30c6\u30ed\u30e1\u30a2\u2015\u305c\u304c\u6d3b\u6027\u5316\u3057\u3066\u3044\u308b\u3068\u306e\u3053\u3068\u306a\u306e\u3067\u3001\u3046\u3063\u304b\u308a\u300c\u82e5\u8fd4\u308a\u300d\u306e\u3064\u3082\u308a\u3067\u30c6\u30ed\u30e1\u30a2\u2015\u305c\u6d3b\u6027\u5316\u85ac\u3092\u98f2\u3093\u3060\u3089\u3068\u3093\u3067\u3082\u306a\u3044\u3053\u3068\u306b\u306a\u308a\u305d\u3046\u3067\u3059\u3002\u9006\u306b\u3001\u30c6\u30ed\u30e1\u30a2\u2015\u305c\u963b\u5bb3\u5264\u306f\u6297\u304c\u3093\u5264\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u305d\u308c\u308220\u5e74\u8fd1\u304f\u7814\u7a76\u3055\u308c\u3066\u304d\u3066\u3044\u3066\u3001\u4eca\u81e8\u5e8a\u8a66\u9a13\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u9b54\u6cd5\u306e\u85ac\u52b9\u306f\u306a\u3044\u3088\u3046\u3067\u3001\u9650\u5b9a\u3055\u308c\u305f\u9aa8\u9ac4\u816b\u306a\u3069\u3067\u6709\u52b9\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u7a0b\u5ea6\u3067\u3059\u3002\u8840\u6db2\u5e79\u7d30\u80de\u304c\u5206\u88c2\u3067\u304d\u306a\u304f\u306a\u308b\u3068\u305f\u3044\u3078\u3093\u306a\u306e\u3067\uff08\u2192\u81f4\u6b7b\u6027\u306e\u60aa\u6027\u8ca7\u8840\uff09\u3001\u526f\u4f5c\u7528\u306b\u3082\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3057\u3087\u3046\u3002
\nhttps:\/\/www.geron.com\/research-and-development\/telomerase-inhibition\/
\nhttps:\/\/en.wikipedia.org\/wiki\/Imetelstat<\/p>\n
\u82f1\u8a9e\u306f\u9069\u5f53\u306b\u9078\u3093\u3067\u307f\u307e\u3059\u3002
\ntelomere \u300c\u30c6\u300d\u308d\u30df\u30a2
\neukaryotic \u30e6\u30fc\u30ab\u30ea\u30aa\u30c6\u30a3\u30c3\u30af\u3000\u771f\u6838\u751f\u7269\u306e
\nchromosome \u30af\u300c\u30ed\u300d\u30e2\u30bd\u30fc\u30e0\u3000\u67d3\u8272\u4f53
\nmonochrome \u30e2\u30ce\u30af\u30ed\u3000\uff1d\u767d\u9ed2\u753b\u50cf
\nchromium \u30af\u30ed\u30e0\uff08\u5143\u7d20\uff09\u3000\u3044\u308d\u3044\u308d\u306a\u8272\u306e\u5316\u5408\u7269\u304c\u3042\u308b\u304b\u3089\u547d\u540d\u3055\u308c\u307e\u3057\u305f
\nsomatic cell division \u4f53\u7d30\u80de\u5206\u88c2
\nimmortal tissues \u4e0d\u6b7b\u6027\u306e\u7d44\u7e54
\n“During DNA replication, DNA polymerase cannot replicate the sequences present at the 3’ ends of the parent strands. ”
\nreplication \u8907\u88fd
\nparent strands \u89aa\u914d\u5217
\n\u5965\u6b6f\u306b\u3082\u306e\u304c\u631f\u307e\u3063\u305f\u3088\u3046\u306a\u8a00\u3044\u65b9\u3000talk\/write as if the one\/author were hiding something
\nsenescence \u30bb\u30cd\u30bb\u30f3\u30b9\u3000\u8001\u5316
\nsenator \u5143\u8001\u9662\u8b70\u54e1\u3001\u4e0a\u9662\u8b70\u54e1\u3001\u8a55\u8b70\u54e1\u3001\u5dde\u8b70\u4f1a\u8b70\u54e1
\nsenate \u5143\u8001\u9662\u3001\u4e0a\u9662\u3001\u8a55\u8b70\u4f1a\u3001\u5dde\u8b70\u4f1a<\/p>\n","protected":false},"excerpt":{"rendered":"
\u7d30\u80de\u5206\u88c2\u306e\u56de\u6570\u3092\u5236\u9650\u3059\u308bHayflick limit\uff08\u4eba\u9593\u306e\u4f53\u7d30\u80de\u306f\u7d0450\u56de\uff09\u306e\u4ed5\u7d44\u307f\u306f\u3001\u30c6\u30ed\u30e1\u30a2\u304c\u77ed\u304f\u306a\u308b\u3053\u3068\u3067\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30c6\u30ed\u30e1\u30a2\u306f\u54fa\u4e73\u985e\u3067\u306f(TTAGGG)\u304c\u591a\u6570\u7e70\u308a\u8fd4\u3055\u308c\u305f\u914d\u5217\u304cDNA\u306e\u7aef\u306b\u304f\u3063\u3064\u3044\u3066\u3044\u308b\u3082\u306e\u3067\u3001\u67d3\u8272\u4f53\u3068\u3057\u3066\u307e\u3068\u307e\u308b\u6642\u306e\u672b\u7aef\u306e\u4fdd\u8b77\u306b\u5f79\u7acb\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4e0b\u8a18wikipedia\u306b\u308f\u304b\u308a\u3084\u3059\u3044\u5199\u771f\u304c\u3067\u3066\u3044\u307e\u3059\u3002 https:\/\/en.wikipedia.org\/wiki\/Telomere \u7d30\u80de\u5206\u88c2\u306e\u305f\u3073\u306b\u3001DNA\u3092\u307b\u3069\u3044\u3066\u5168\u30b3\u30d4\u30fc\u3059\u308b\u3068\u304d\u306b\u7aef\u304c\u3069\u3046\u3057\u3066\u3082\u30b3\u30d4\u30fc\u3067\u304d\u306a\u3044\u305f\u3081\u77ed\u304f\u306a\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u751f\u6b96\u7d30\u80de\u3068\u8840\u6db2\u5e79\u7d30\u80de\u306f\u4f8b\u5916\u3067\u3001\u30c6\u30ed\u30e1\u30a2\u3092\u9577\u3044\u72b6\u614b\u306b\u623b\u3059\u30c6…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[46],"tags":[9],"class_list":["post-1762","post","type-post","status-publish","format-standard","hentry","category-bio","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1762"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1762\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1762"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1762"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}