2022\u306e\u30ce\u30fc\u30d9\u30eb\u5316\u5b66\u8cde\u306f”about snapping molecules together” \u306b\u4e0e\u3048\u3089\u308c\u307e\u3057\u305f\u3002click chemistry\uff08\u30af\u30ea\u30c3\u30af\u30b1\u30df\u30b9\u30c8\u30ea\u30fc\uff09\u306f\u3001\u8907\u96d1\u306a\u5206\u5b50\u306b\u7279\u5b9a\u306e\u5b98\u80fd\u57fa\u3092\u3064\u3051\u3066\u304a\u304d\u3001\u305d\u306e\u53cd\u5fdc\u3060\u3051\u304c\u78ba\u5b9f\u306b\u8d77\u3053\u308b\u3053\u3068\u3092\u5229\u7528\u3057\u3066\u3001\u526f\u7523\u7269\u7121\u3057\u306b\u72d9\u3063\u305f\u5206\u5b50\u3060\u3051\u3092\u5171\u6709\u7d50\u5408\u3067\u7d50\u5408\u3055\u305b\u308b\u6982\u5ff5\u3067\u3001\u3044\u305a\u308c\u53d7\u8cde\u3059\u308b\u3060\u308d\u3046\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3057\u305f\u3002Meldal\u6559\u6388\u304c\u6700\u521d\u306e\u6c4e\u7528\u7684\u306a\u53cd\u5fdc\u3092\u767a\u898b\u3057\u3001Sharpless\u6559\u6388\u304c\u4f53\u7cfb\u5316\u3057\u307e\u3057\u305f\u3002Sharpless\u6559\u6388\u306f2001\u5e74\u306b\u91ce\u4f9d\u6559\u6388\u3068\u4e00\u7dd2\u306b\u3059\u3067\u306b\u53d7\u8cde\u3057\u3066\u3044\u308b\u305f\u3081\u30012\u56de\u76ee\u53d7\u8cde\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3001\u3068\u3044\u3046\u8a71\u984c\u304c\u3042\u308a\u307e\u3057\u305f\u304c\u3001\u4eca\u56de\u53d7\u8cde\u3057\u307e\u3057\u305f\u3002
\nhttps:\/\/ja.wikipedia.org\/wiki\/%E3%82%AF%E3%83%AA%E3%83%83%E3%82%AF%E3%82%B1%E3%83%9F%E3%82%B9%E3%83%88%E3%83%AA%E3%83%BC
\n\u751f\u4f53\u3078\u306e\u5fdc\u7528\u304c\u53d7\u8cde\u7406\u7531\u306b\u53d6\u308a\u4e0a\u3052\u3089\u308c\u3066\u3044\u305f\u306e\u306f\u8208\u5473\u6df1\u3044\u3067\u3059\u304c\u3001\u8abf\u3079\u3066\u307f\u308b\u3068\u5275\u85ac\u7b49\u3078\u306e\u5fdc\u7528\u304c\u5e83\u304c\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u539f\u6599\u3068\u306a\u308b\u5206\u5b50\uff08\u4f8b\uff1a\u4eba\u5de5\u7684\u306b\u5408\u6210\u3057\u305f\u30a2\u30b8\u30c9\uff08N3\uff09\u306e\u3064\u3044\u305f\u7cd6\uff09\u3092\u7d30\u80de\u306b\u53d6\u308a\u8fbc\u307e\u305b\u3001\u751f\u7269\u5185\u3067\u53cd\u5fdc\u3055\u305b\u3066\u7d30\u80de\u819c\u306b\u3064\u3051\u3001\u305d\u308c\u304b\u3089\u30af\u30ea\u30c3\u30af\u30b1\u30df\u30b9\u30c8\u30ea\u30fc\u3067\u5225\u306e\u5206\u5b50\u3092\u304f\u3063\u3064\u3051\u308b\u306a\u3069\u3001\u82b8\u8853\u7684\u3067\u5fdc\u7528\u3082\u5e83\u305d\u3046\u3067\u3059\u3002\u4e0b\u8a18\u306f\u7d30\u80de\u819c\u4e2d\u306e\u7279\u5b9a\u306e\u5206\u5b50\u306b\u86cd\u5149\u8272\u7d20\u3092\u304f\u3063\u3064\u3051\u3066\u3044\u307e\u3059\u3002\u975e\u5e38\u306b\u7c21\u6f54\u306a\u8ad6\u6587\u3067\u3059\u304c\u3001\u4eca\u56de\u306e\u53d7\u8cde\u6982\u5ff5\u306e\u5206\u304b\u308a\u3084\u3059\u3044\u4f8b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/www.science.org\/doi\/10.1126\/science.287.5460.2007
\n\u4e0a\u8a18\u8ad6\u6587\u306e\u53cd\u5fdc\u306fStaudinger-Bertozzi\u53cd\u5fdc\u3068\u3044\u3046\u540d\u524d\u304c\u3064\u3044\u3066\u3044\u307e\u3059\u3002\u8457\u8005\u306eBertozzi\u6559\u6388\u3082\u4eca\u56de\u53d7\u8cde\u3057\u307e\u3057\u305f\u3002
\nhttps:\/\/www.chem-station.com\/odos\/2009\/06\/staudinger.html<\/p>\n
\u82f1\u8a9e\u306f\u4e0a\u8a18\u8ad6\u6587\u304b\u3089\u3002<\/p>\n
snap together \u565b\u307f\u3042\u3063\u3066\u304f\u3063\u3064\u304f<\/p>\n
elucidate \u30a8\u300c\u308b\u300d\u30b9\u30a3\u30c7\u30a4\u30c8\u3000\u89e3\u660e\u3059\u308b
\nligation \u3089\u30a4\u30b2\u30fc\u30b7\u30e7\u30f3\u3000\u7d50\u7d2e\uff08\u3051\u3063\u3055\u3064\uff09\u3001\u9023\u7d50\u3001\u5316\u5b66\u7d50\u5408\u3067\u304f\u3063\u3064\u3051\u308b
\nmetabolism\u3000\u4ee3\u8b1d\u3000\u300c\u30e1\u30bf\u30dc\u300d\u3067\u3059
\naugment \u30aa\u30fc\u30b0\u300c\u30e1\u300d\u30f3\u30c8\u3000\u62e1\u5f35\u3059\u308b
\nHeLa cell \u30d2\u30fc\u30e9\u7d30\u80de\u3000\uff08\u5b9f\u9a13\u7528\u306b\u58f2\u3063\u3066\u3044\u308b\u3001\u5897\u3084\u3057\u3084\u3059\u3044\u4eba\u9593\u306e\u7d30\u80de\u3002\u3082\u3068\u306f\u4eba\u306e\u4e73\u304c\u3093\u7d30\u80de\uff09
\nJurkat cell\u3000\u30b8\u30e5\u30eb\u30ab\u30c3\u30c8\u7d30\u80de \uff08\u5b9f\u9a13\u7528\u306b\u58f2\u3063\u3066\u3044\u308b\u3001T\u7d30\u80de\u767d\u8840\u75c5\u306e\u30ea\u30f3\u30d1\u7d30\u80de\u3002\u3053\u308c\u3082\u4eba\u7531\u6765\u3067\u3059\uff09
\npredominant pathway \u652f\u914d\u7684\u306a\u7d4c\u8def
\nbiotin \u30d3\u30aa\u30c1\u30f3\u3000https:\/\/ja.wikipedia.org\/wiki\/%E3%83%93%E3%82%AA%E3%83%81%E3%83%B3
\n\u3000\u30d3\u30bf\u30df\u30f3B7\u3002\u30a2\u30d3\u30b8\u30f3\u3068\u306e\u89aa\u548c\u6027\u3092\u5229\u7528\u3057\u3066\u3044\u308d\u3044\u308d\u306a\u5b9f\u9a13\u306b\u4f7f\u3044\u307e\u3059\u3002\u7d30\u83cc\u304c\u4f7f\u3063\u3066\u3044\u308b\u3068\u306e\u3053\u3068\u3002
\navidin \u30a2\u30d3\u30b8\u30f3\u3000https:\/\/ja.wikipedia.org\/wiki\/%E3%82%A2%E3%83%93%E3%82%B8%E3%83%B3
\n\u3000\u751f\u306e\u5375\u767d\u4e2d\u306b\u3042\u308b\u30d3\u30aa\u30c1\u30f3\u3068\u5f37\u304f\u7d50\u5408\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3002\u7d30\u83cc\u306e\u6210\u9577\u3092\u963b\u5bb3\u3059\u308b\u5f79\u5272\u3068\u3044\u3046\u306e\u306f\u77e5\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"
2022\u306e\u30ce\u30fc\u30d9\u30eb\u5316\u5b66\u8cde\u306f”about snapping molecules together” \u306b\u4e0e\u3048\u3089\u308c\u307e\u3057\u305f\u3002click chemistry\uff08\u30af\u30ea\u30c3\u30af\u30b1\u30df\u30b9\u30c8\u30ea\u30fc\uff09\u306f\u3001\u8907\u96d1\u306a\u5206\u5b50\u306b\u7279\u5b9a\u306e\u5b98\u80fd\u57fa\u3092\u3064\u3051\u3066\u304a\u304d\u3001\u305d\u306e\u53cd\u5fdc\u3060\u3051\u304c\u78ba\u5b9f\u306b\u8d77\u3053\u308b\u3053\u3068\u3092\u5229\u7528\u3057\u3066\u3001\u526f\u7523\u7269\u7121\u3057\u306b\u72d9\u3063\u305f\u5206\u5b50\u3060\u3051\u3092\u5171\u6709\u7d50\u5408\u3067\u7d50\u5408\u3055\u305b\u308b\u6982\u5ff5\u3067\u3001\u3044\u305a\u308c\u53d7\u8cde\u3059\u308b\u3060\u308d\u3046\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3057\u305f\u3002Meldal\u6559\u6388\u304c\u6700\u521d\u306e\u6c4e\u7528\u7684\u306a\u53cd\u5fdc\u3092\u767a\u898b\u3057\u3001Sharpless\u6559\u6388\u304c\u4f53\u7cfb\u5316\u3057\u307e\u3057\u305f\u3002Sharpless\u6559\u6388\u306f2001\u5e74\u306b\u91ce\u4f9d\u6559\u6388\u3068\u4e00\u7dd2\u306b\u3059\u3067\u306b\u53d7\u8cde\u3057\u3066\u3044\u308b\u305f\u3081\u30012\u56de\u76ee\u53d7\u8cde\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3001\u3068\u3044\u3046\u8a71\u984c\u304c\u3042\u308a\u307e\u3057\u305f\u304c\u3001\u4eca\u56de\u53d7\u8cde\u3057\u307e…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[41,44,46],"tags":[4,7,9],"class_list":["post-1560","post","type-post","status-publish","format-standard","hentry","category-historicalfigures","category-materials","category-bio","tag-historicalfigures","tag-materials","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1560","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1560"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1560\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1560"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1560"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}