\u4eba\u9593\u306e\u6301\u3064\u907a\u4f1d\u60c5\u5831(human genome \u30d2\u30c8\u30b2\u30ce\u30e0\uff09\u306f30\u5104\u5869\u57fa\u5bfe\u3001750MB\u3060\u305d\u3046\u3067\u3059\u3002USB\u30e1\u30e2\u30ea\u306b\u4f59\u88d5\u3067\u5165\u308b\u91cf\u306a\u306e\u3067\u610f\u5916\u3068\u5c11\u306a\u3044\u3088\u3046\u306b\u601d\u3044\u307e\u3059\u304c\u3001\u4e00\u3064\u4e00\u3064\u898b\u3066\u3044\u304f\u3068\u6c17\u304c\u9060\u304f\u306a\u308a\u305d\u3046\u3067\u3059\u3002\u305d\u306e\u3046\u3061\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u308b\u90e8\u5206\u306f\u7d0430000\u7a2e\u985e\u3068\u8a00\u308f\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u307b\u304b\u306b\u3001\u767a\u73fe\u306e\u5236\u5fa1\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u6761\u4ef6\u6587\uff08\u3069\u306e\u3088\u3046\u306a\u6761\u4ef6\u306e\u3068\u304d\u3069\u306e\u304f\u3089\u3044\u305d\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f5c\u308b\u304b,\u5178\u578b\u7684\u306a\u52d5\u4f5c\u901f\u5ea6\u306f20\u5206\u3068\u805e\u304d\u307e\u3057\u305f\uff09\u306a\u3069\u3082\u66f8\u304d\u8fbc\u307e\u308c\u3066\u3044\u308b\u3068\u3044\u3046\u306e\u304c\u79c1\u306e\u7406\u89e3\u3067\u3059\u3002\u3053\u308c\u3092\u8abf\u3079\u308c\u3070\u88fd\u85ac\u306b\u5f79\u7acb\u3064\u306e\u306f\u9593\u9055\u3044\u306a\u3044\u306e\u3067\u3001\u591a\u304f\u306e\u4eba\u304c\u7814\u7a76\u306b\u5f93\u4e8b\u3057\u3066\u3044\u307e\u3059\u3002\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30a3\u30c3\u30af\u30b9\u306f\u3001\u6700\u8fd1\u306e\u30c7\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3\u30b9\u306e\u5148\u99c6\u3051\u3068\u306a\u3063\u305f\u5206\u91ce\u3067\u3059\u3002
\n\u30d2\u30c8\u30b2\u30ce\u30e0\u306e\u4e2d\u3067\u3001\u500b\u6027\u3092\u8868\u3059\u90e8\u5206(single nucleotide polytypes SNPs\u3000\u30b9\u30cb\u30c3\u30d7\u30b9)\u306f\u7d041000\u5869\u57fa\u306b\u4e00\u3064\u3060\u305d\u3046\u306a\u306e\u306730\u5104\u00f71000=300\u4e07\u500b\u306e\u5909\u5316\u304c\u3042\u308a\uff08wikipedia\u3067\u306f\u901a\u5e384~500\u4e07\u304b\u6240\u3067\u3001\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u306f\u7a00\u306a\u3082\u306e\u3092\u5165\u308c\u3066\uff1f3\u51043500\u4e07\u7b87\u6240\u4ee5\u4e0a\u3068\u3042\u308a\u307e\u3059\uff09\u3001\u305d\u308c\u305e\u308c\u304cATCG\u306e4\u7a2e\u985e\u306a\u306e\u3067\u3001\u5358\u7d14\u306b\u8003\u3048\u308b\u30684^(3×10^6) =10^1800000\u3067\u300110\u9032\u6570\u3067180\u4e07\u30b1\u30bf\u306e\u500b\u6027\u304c\u907a\u4f1d\u5b50\u30ec\u30d9\u30eb\u3067\u5b58\u5728\u3067\u304d\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u306d\u3002SNPs\u306f\u3059\u3079\u3066\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u53ef\u80fd\u3067\u306f\u306a\u3044\u3088\u3046\u306a\u306e\u3067\u305a\u3063\u3068\u6e1b\u308b\u3068\u601d\u3044\u307e\u3059\u304c\u3001\u305d\u308c\u3067\u3082\u4eba\u9593\u306f\u907a\u4f1d\u5b50\u30ec\u30d9\u30eb\u3067\u4e8b\u5b9f\u4e0a\u7121\u9650\u306e\u500b\u6027\u304c\u3042\u308b\u3068\u8a00\u3063\u3066\u3044\u3044\u3068\u601d\u3044\u307e\u3059\u3002
\nhttps:\/\/ja.wikipedia.org\/wiki\/%E4%B8%80%E5%A1%A9%E5%9F%BA%E5%A4%9A%E5%9E%8B
\nhttps:\/\/en.wikipedia.org\/wiki\/Single-nucleotide_polymorphism
\n\u4e0b\u8a18\u306f\u30b2\u30ce\u30e0\u306b\u95a2\u3057\u3066\u4e00\u822c\u5411\u3051\u306e\u60c5\u5831\u304c\u591a\u304f\u52c9\u5f37\u306b\u306a\u308b\u30b5\u30a4\u30c8\u3067\u3059(\u6771\u5317\u5927\u304c\u3064\u304f\u3063\u3066\u3044\u307e\u3059\uff09\u3002
\nhttps:\/\/www.megabank.tohoku.ac.jp\/genome\/archives\/category\/darwinian<\/p>\n
base pair \u5869\u57fa\u5bfe
\nnucleotide \u30cc\u30af\u30aa\u30ec\u30c1\u30c9\u3000\u3053\u308c\u304c\u3064\u306a\u304c\u3063\u3066\u6838\u9178(nucleic acid= DNA\u3068RNA)\u306b\u306a\u308b
\npolymorphism \u591a\u578b
\nfraction \u4e00\u90e8\u3001\u90e8\u5206
\nan allele \u300c\u30a2\u300d\u30ec\u30ea\u3000\u5bfe\u7acb\u907a\u4f1d\u5b50\uff08weblio \u30ec\u30d9\u30eb12)\u3000\u2190\u3053\u308c\u306f5500\u8a9e\u30ec\u30d9\u30eb\u3002\u77e5\u308a\u307e\u305b\u3093\u3067\u3057\u305f
\nmanifestation\u3000\u5146\u5019\u3001\u73fe\u308c\u3001\u8868\u660e
\n The way the body responds to treatments are also manifestations of genetic variations caused by SNPs.
\nsomatic cells \u4f53\u7d30\u80de \u3000somatic\u3000\u8eab\u4f53\u306e\u3000\u30bd\u300c\u30de\u300d\u30c6\u30a3\u30c3\u30af\uff08\u30ec\u30d9\u30eb12)
\ngerm cells \u80da\u7d30\u80de\u3000(germ \u30b8\u30e3\u30fc\u30e0 \u306f\u3000\u80da\u3001\u7d30\u83cc\u3001\u3070\u3044\u83cc\u306e\u610f\u5473\u304c\u3042\u308a\u307e\u3059)\u3000= sperm \u30b9\u300c\u30d1\u30fc\u300d\u30e0\u3000\u7cbe\u5b50\u3000+ ovum(egg)\u3000\u300c\u30aa\u30a6\u300d\u30f4\u30a1\u30e0\u3000\u5375\u5b50
\ndiagnostics \u8a3a\u65ad\u3000\u30c0\u30a4\u30a2\u30b0\u300c\u30ce\u300d\u30b9\u30c6\u30a3\u30c3\u30af\u30b9
\ncohort \u75ab\u5b66\u7d71\u8a08\u306a\u3069\u306e\u96c6\u56e3\u3001\uff08\u7c73\uff09\u4ef2\u9593\u30fb\u76f8\u68d2\u3000\u300c\u30b3\u30a6\u300d\u30db\u30fc\u30c8 (\u30ec\u30d9\u30eb10\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"
\u4eba\u9593\u306e\u6301\u3064\u907a\u4f1d\u60c5\u5831(human genome \u30d2\u30c8\u30b2\u30ce\u30e0\uff09\u306f30\u5104\u5869\u57fa\u5bfe\u3001750MB\u3060\u305d\u3046\u3067\u3059\u3002USB\u30e1\u30e2\u30ea\u306b\u4f59\u88d5\u3067\u5165\u308b\u91cf\u306a\u306e\u3067\u610f\u5916\u3068\u5c11\u306a\u3044\u3088\u3046\u306b\u601d\u3044\u307e\u3059\u304c\u3001\u4e00\u3064\u4e00\u3064\u898b\u3066\u3044\u304f\u3068\u6c17\u304c\u9060\u304f\u306a\u308a\u305d\u3046\u3067\u3059\u3002\u305d\u306e\u3046\u3061\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u308b\u90e8\u5206\u306f\u7d0430000\u7a2e\u985e\u3068\u8a00\u308f\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u307b\u304b\u306b\u3001\u767a\u73fe\u306e\u5236\u5fa1\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u6761\u4ef6\u6587\uff08\u3069\u306e\u3088\u3046\u306a\u6761\u4ef6\u306e\u3068\u304d\u3069\u306e\u304f\u3089\u3044\u305d\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f5c\u308b\u304b,\u5178\u578b\u7684\u306a\u52d5\u4f5c\u901f\u5ea6\u306f20\u5206\u3068\u805e\u304d\u307e\u3057\u305f\uff09\u306a\u3069\u3082\u66f8\u304d\u8fbc\u307e\u308c\u3066\u3044\u308b\u3068\u3044\u3046\u306e\u304c\u79c1\u306e\u7406\u89e3\u3067\u3059\u3002\u3053\u308c\u3092\u8abf\u3079\u308c\u3070\u88fd\u85ac\u306b\u5f79\u7acb\u3064\u306e\u306f\u9593\u9055\u3044\u306a\u3044\u306e\u3067\u3001\u591a\u304f\u306e\u4eba\u304c\u7814\u7a76\u306b\u5f93\u4e8b\u3057\u3066\u3044\u307e\u3059\u3002\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30a3\u30c3\u30af\u30b9\u306f\u3001\u6700\u8fd1\u306e\u30c7\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3\u30b9\u306e\u5148\u99c6\u3051\u3068\u306a\u3063\u305f…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[42,46],"tags":[5,9],"class_list":["post-1166","post","type-post","status-publish","format-standard","hentry","category-tech","category-bio","tag-tech","tag-bio"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1166","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1166"}],"version-history":[{"count":0,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=\/wp\/v2\/posts\/1166\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1166"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1166"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sekaiken.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1166"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}